{"doi":"10.1093/scan/nsae052","title":"Loneliness and brain rhythmic activity in resting state: an exploratory report","abstract":"<jats:title>Abstract</jats:title>\n               <jats:p>Recent studies using resting-state functional magnetic resonance imaging have shown that loneliness is associated with altered blood oxygenation in several brain regions. However, the relationship between loneliness and changes in neuronal rhythm activity in the brain remains unclear. To evaluate brain rhythm, we conducted an exploratory resting-state electroencephalogram (EEG) study of loneliness. We recorded resting-state EEG signals from 139 participants (94 women; mean age = 19.96 years) and analyzed power spectrum density (PSD) and functional connectivity (FC) in both the electrode and source spaces. The PSD analysis revealed significant correlations between loneliness scores and decreased beta-band powers, which may indicate negative emotion, attention, reward, and/or sensorimotor processing. The FC analysis revealed a trend of alpha-band FC associated with individuals’ loneliness scores. These findings provide new insights into the neural basis of loneliness, which will facilitate the development of neurobiologically informed interventions for loneliness.</jats:p>","journal":"Social Cognitive and Affective Neuroscience","year":2024,"id":653817,"datarank":0.25712456221891206,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.015708875353796985,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.015708875353796985,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":4,"citers_with_citation_signal":2,"citers_with_endowment":2,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1706021,"name":"Xufang Wang","orcid":null,"position":1,"is_corresponding":false},{"id":1662549,"name":"Changquan Long","orcid":"0000-0002-6074-2423","position":2,"is_corresponding":false},{"id":866028,"name":"Xu Lei","orcid":"0000-0003-2271-1287","position":3,"is_corresponding":false},{"id":1103112,"name":"Xin Hu","orcid":"0000-0002-3253-6024","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Loneliness and brain rhythmic activity in resting state: an exploratory report","abstract":"Recent studies using resting-state functional magnetic resonance imaging have shown that loneliness is associated with altered blood oxygenation in several brain regions. However, the relationship between loneliness and changes in neuronal rhythm activity in the brain remains unclear. To evaluate brain rhythm, we conducted an exploratory resting-state electroencephalogram (EEG) study of loneliness. We recorded resting-state EEG signals from 139 participants (94 women; mean age = 19.96 years) and analyzed power spectrum density (PSD) and functional connectivity (FC) in both the electrode and source spaces. The PSD analysis revealed significant correlations between loneliness scores and decreased beta-band powers, which may indicate negative emotion, attention, reward, and/or sensorimotor processing. The FC analysis revealed a trend of alpha-band FC associated with individuals' loneliness scores. These findings provide new insights into the neural basis of loneliness, which will facilitate the development of neurobiologically informed interventions for loneliness.","is_dataset_classified":null,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"39096513","pmcid":"PMC11374414","openalex_id":"https://openalex.org/W4401282950","authors":[],"funders":[{"funder_name":"National Natural Science Foundation of China","grant_id":"31971028","title":null},{"funder_name":"Fundamental Research Funds for the Central Universities","grant_id":"SWU2209240","title":null},{"funder_name":"Research and Development Program of China","grant_id":"2021YFC2501500","title":null}],"total_grants":3,"fwci":0.9424,"citation_percentile":0.72018119,"influential_citations":0,"citation_trend":[{"year":2025,"count":4}],"oa_status":"gold","license":"cc-by-nc","oa_locations":[{"url":"https://academic.oup.com/scan/advance-article-pdf/doi/10.1093/scan/nsae052/58728181/nsae052.pdf","host_type":"journal"},{"url":"https://academic.oup.com/scan/advance-article-pdf/doi/10.1093/scan/nsae052/58728181/nsae052.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1093/scan/nsae052","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/39096513","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11374414","host_type":"repository"},{"url":"https://osf.io/txc3b","host_type":"repository"},{"url":"https://osf.io/xt3pk","host_type":"repository"},{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11374414/pdf/nsae052.pdf","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC11374414","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC11374414?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Functional Brain Connectivity Studies","Heart Rate Variability and Autonomic Control","Neural and Behavioral Psychology Studies","Humans","Female","Loneliness","Male","Brain","Young Adult","Electroencephalography","Rest","Adult","Adolescent","Brain Waves","Brain Mapping"],"mesh_terms":["Adolescent","Adult","Brain","Brain Mapping","Electroencephalography","Female","Humans","Loneliness","Male","Rest","Young Adult","Brain Waves"],"keywords":["Loneliness","Psychology","Resting state fMRI","Brain activity and meditation","Functional magnetic resonance imaging","Electroencephalography","Rhythm","Psychological intervention","Audiology","Neuroscience","Developmental psychology","Psychiatry","Medicine","Internal medicine","Electroencephalogram (Eeg)","Perceived Social Isolation","Lonely","Alpha-band Functional Connectivity","Beta-band Powers"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Gender equality"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-11T01:08:28.926745Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}