{"doi":"10.1093/pubmed/fdac038","title":"Tackling barriers to COVID-19 vaccine uptake in London: a mixed-methods evaluation","abstract":"BACKGROUND: In response to the COVID-19 pandemic, the first vaccine was administered in December 2020 in England. However, vaccination uptake has historically been lower in London than in other English regions. METHODS: Mixed-methods: This comprised an analysis of cumulative percentage uptake across London between 8 December 2020 and 6 June 2021 by vaccine priority cohorts and ethnicity. We also undertook thematic analyses of uptake barriers, interventions to tackle these and key learning from a qualitative survey of 27 London local authority representatives, vaccine plans from London's five Integrated Care Systems and interviews with 38 London system representatives. RESULTS: Vaccine uptake was lower in Black ethnic (57-65% uptake) compared with the White British group (90% uptake). Trust was a critical issue, including mistrust in the vaccine itself and in authorities administering or promoting it. The balance between putative costs and benefits of vaccination created uptake barriers for zero-hour and shift workers. Intensive, targeted and 'hyper-local' initiatives, which sustained community relationships and were not constrained by administrative boundaries, helped tackle these barriers. CONCLUSIONS: The success of the national vaccination programme depended on conceding local autonomy, investing in responsive and long-term partnerships to engender trust through in-depth understanding of communities' beliefs.","journal":"Journal of Public Health","year":2022,"id":268655,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":23,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7648,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":930845,"name":"Jenny Shand","orcid":"0000-0002-4899-795X","position":1,"is_corresponding":false},{"id":930846,"name":"Leonora G Weil","orcid":"0000-0002-1447-7155","position":2,"is_corresponding":false},{"id":842541,"name":"Andrew Hutchings","orcid":"0000-0003-0215-9923","position":3,"is_corresponding":false},{"id":931446,"name":"Ana Zuriaga","orcid":null,"position":4,"is_corresponding":false},{"id":931447,"name":"Dane Satterthwaite","orcid":null,"position":5,"is_corresponding":false},{"id":930847,"name":"Jennifer Yip","orcid":"0009-0004-6413-9623","position":6,"is_corresponding":false},{"id":931448,"name":"Cyril Eshareturi","orcid":null,"position":7,"is_corresponding":false},{"id":931449,"name":"Julie Billett","orcid":null,"position":8,"is_corresponding":false},{"id":931450,"name":"Ann Hepworth","orcid":null,"position":9,"is_corresponding":false},{"id":931451,"name":"Rakesh Dodhia","orcid":null,"position":10,"is_corresponding":false},{"id":931452,"name":"Ellen Schwartz","orcid":null,"position":11,"is_corresponding":false},{"id":931453,"name":"Rachel Penniston","orcid":null,"position":12,"is_corresponding":false},{"id":931454,"name":"Emma Mordaunt","orcid":null,"position":13,"is_corresponding":false},{"id":931455,"name":"Sophie Bulmer","orcid":null,"position":14,"is_corresponding":false},{"id":930848,"name":"Helen Barratt","orcid":"0000-0002-1387-137X","position":15,"is_corresponding":false},{"id":931456,"name":"John Illingworth","orcid":null,"position":16,"is_corresponding":false},{"id":931457,"name":"J. Hampden Inskip","orcid":null,"position":17,"is_corresponding":false},{"id":930849,"name":"Fran Bury","orcid":"0000-0002-6305-1994","position":18,"is_corresponding":false},{"id":930850,"name":"Deborah Jenkins","orcid":"0000-0002-4083-2579","position":19,"is_corresponding":false},{"id":16205,"name":"Sandra Mounier‐Jack","orcid":"0000-0002-2801-379X","position":20,"is_corresponding":false},{"id":539327,"name":"Rosalind Raine","orcid":"0000-0003-0904-749X","position":21,"is_corresponding":false},{"id":930844,"name":"Kristoffer Halvorsrud","orcid":"0000-0002-8813-0939","position":0,"is_corresponding":true}],"reference_count":10,"raw_metadata":null,"created_at":"2026-07-19T00:27:14.088663Z","pmid":"35373295","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}