{"doi":"10.1093/ofid/ofae660","title":"Development of a City-wide Rapid Antiretroviral Therapy Initiation Toolkit for People Newly Diagnosed With HIV in the Southern United States","abstract":"Background: Rapid antiretroviral therapy (ART) initiation, in which individuals with HIV start treatment within days of diagnosis, is a key component of the United States (US) Ending the HIV Epidemic initiative. The Memphis Metropolitan Statistical Area ranks second in the US for HIV incidence, yet only ∼60% of individuals link to treatment within 1 month of diagnosis. This study aimed to identify barriers and strategies for implementing rapid ART initiation in Memphis. Methods: From August to December 2022, we conducted process mapping guided by the Consolidated Framework for Implementation Research to outline the steps from 3 HIV testing sites to ART prescription at 3 Ryan White-funded clinics in Memphis, Tennessee. We used modified conjoint analyses to prioritize barriers and identify strategies for improving rapid ART implementation, focusing on the importance and feasibility of changes. Findings: Prioritized barriers included intersectional stigma and a lack of access to centralized information about the rapid ART program, branding and logo development, inter- and intra-organizational networking and communication, testing and treatment resources (HIV testing kits and ART starter packs), rapid ART knowledge, and organizational champions. Strategies to address these barriers were compiled into a local rapid ART toolkit. Conclusions: We identified modifiable systemic barriers to rapid ART initiation in Memphis, a community disproportionately affected by HIV. The strategies developed to address these barriers informed the creation of a locally relevant rapid ART toolkit for future evaluation. These methods could be applied in other high-burden areas seeking to develop local rapid ART models.","journal":"Open Forum Infectious Diseases","year":2024,"id":506401,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.953,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1357934,"name":"Aimalohi A. Ahonkhai","orcid":null,"position":1,"is_corresponding":false},{"id":572733,"name":"Leslie Pierce","orcid":"0009-0001-4566-9969","position":2,"is_corresponding":false},{"id":240239,"name":"Peter F. Rebeiro","orcid":"0000-0003-1951-9104","position":3,"is_corresponding":false},{"id":1357935,"name":"Cristobal Mario Valdebenito","orcid":null,"position":4,"is_corresponding":false},{"id":1357608,"name":"Jennifer Woods","orcid":"0000-0003-2793-0390","position":5,"is_corresponding":false},{"id":1357936,"name":"L Gregory","orcid":null,"position":6,"is_corresponding":false},{"id":1357609,"name":"Chris Walton","orcid":"0000-0002-8037-5616","position":7,"is_corresponding":false},{"id":1357937,"name":"Rachel Nash","orcid":null,"position":8,"is_corresponding":false},{"id":370021,"name":"Nathan A. Summers","orcid":"0000-0002-1979-9313","position":9,"is_corresponding":false},{"id":1357938,"name":"A Van Wylen","orcid":null,"position":10,"is_corresponding":false},{"id":453349,"name":"Debbe Thompson","orcid":"0000-0002-5491-8816","position":11,"is_corresponding":false},{"id":1357939,"name":"M Hayes-Winton","orcid":null,"position":12,"is_corresponding":false},{"id":1357610,"name":"Agatha Eke","orcid":"0000-0002-3649-7552","position":13,"is_corresponding":false},{"id":376782,"name":"Latrice C. Pichon","orcid":"0000-0002-2035-8267","position":14,"is_corresponding":false},{"id":371561,"name":"Carolyn M. Audet","orcid":"0000-0002-4715-1346","position":15,"is_corresponding":false},{"id":346880,"name":"April C. Pettit","orcid":"0000-0001-8832-0866","position":0,"is_corresponding":true}],"reference_count":16,"raw_metadata":null,"created_at":"2026-07-19T02:10:54.646711Z","pmid":"39679356","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}