{"doi":"10.1093/ofid/ofae144","title":"Concurrent Administration of COVID-19 and Influenza Vaccines Enhances Spike-Specific Antibody Responses","abstract":"Background: The bivalent COVID-19 mRNA boosters became available in fall 2022 and were recommended alongside the seasonal influenza vaccine. However, the immunogenicity of concurrent vs separate administration of these vaccines remains unclear. Methods: Here, we analyzed antibody responses in health care workers who received the bivalent COVID-19 booster and the influenza vaccine on the same day or on different days through systems serology. Antibody-binding and functional responses were characterized at peak responses and after 6 months following vaccination. Results: IgG1 and neutralization responses to SARS-CoV-2 XBB.1.5 were higher at peak and after 6 months following concurrent administration as compared with separate administration of the COVID-19 and influenza vaccines. While similar results were not observed for influenza responses, no interference was noted with concurrent administration. Conclusions: These data suggest that concurrent administration of these vaccines may yield higher and more durable SARS-CoV-2 neutralizing antibody responses while maintaining responses against influenza.","journal":"Open Forum Infectious Diseases","year":2024,"id":434958,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":12,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.96,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":987502,"name":"Taras M. Chicz","orcid":"0000-0002-5204-2507","position":1,"is_corresponding":false},{"id":1169869,"name":"Ross Blanc","orcid":"0009-0007-9984-5132","position":2,"is_corresponding":false},{"id":1170386,"name":"Domenic R Barbati","orcid":null,"position":3,"is_corresponding":false},{"id":1170387,"name":"Lily J. Parker","orcid":null,"position":4,"is_corresponding":false},{"id":805295,"name":"Xin Tong","orcid":"0000-0001-8024-2357","position":5,"is_corresponding":false},{"id":282756,"name":"Wenjun Li","orcid":"0000-0001-5335-7386","position":6,"is_corresponding":false},{"id":302984,"name":"Ryan P. McNamara","orcid":"0000-0002-8866-3532","position":7,"is_corresponding":false},{"id":1170385,"name":"Susanna E Barouch","orcid":null,"position":0,"is_corresponding":true}],"reference_count":40,"raw_metadata":null,"created_at":"2026-07-19T01:59:58.582186Z","pmid":"38567194","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}