{"doi":"10.1093/ofid/ofad392","title":"A Brief Peer-Led Intervention to Increase COVID-19 Vaccine Uptake Among People Who Inject Drugs in San Diego County: Results From a Pilot Randomized Controlled Trial","abstract":"Abstract Background We evaluated the impact of a brief peer-led intervention on COVID-19 vaccination among people who inject drugs (PWID) presenting at syringe services program (SSP) locations in San Diego County, California. Methods Between March and July 2022, PWID aged ≥18 years without recent voluntary COVID-19 testing who were not up to date on COVID-19 vaccinations received a single-session motivational interviewing intervention (LinkUP) or an attention-matched didactic control condition from trained peer counselors at SSP sites randomized by week. Following either 30-minute session, counselors offered referrals to local vaccination services. Multivariable log binomial regression via generalized estimating equations assessed LinkUP effects on (1) acceptance of COVID-19 vaccination referrals immediately postintervention and (2) COVID-19 vaccine uptake at 6-month follow-up. Results COVID-19 vaccination outcomes were obtained on 135 (90.6%) of 149 participants. In multivariable analysis, participants receiving LinkUP had greater acceptance of COVID-19 vaccination referrals than controls (adjusted relative risk, 3.50; 95% CI, 1.01–12.2) and were marginally more likely to report receiving a new COVID-19 vaccine dose (adjusted relative risk, 1.57; 95% CI, .99–2.48). After 6 months, 20% reported receiving a new vaccine dose; however, if COVID-19 vaccine had been available at SSPs, this proportion could have been as high as 34.3% (45.3% LinkUP vs 24.3% control; P = .01). Conclusions A brief peer-led SSP-based intervention significantly improved COVID-19 vaccination among PWID. Further improvements could likely be obtained by supporting SSPs to offer COVID-19 vaccination on-site instead of relying on referrals. Clinical Trials Registration ClinicalTrials.gov NCT05181657.","journal":"Open Forum Infectious Diseases","year":2023,"id":348138,"datarank":0.42506404942165654,"base_score":2.4849066497880004,"endowment":2.4849066497880004,"self_citation_contribution":0.37273599746820013,"citation_network_contribution":0.05232805195345639,"self_endowment_contribution":0.37273599746820013,"citer_contribution":0.05232805195345639,"corpus_percentile":null,"corpus_rank":null,"citation_count":11,"citer_count":9,"citers_with_citation_signal":2,"citers_with_endowment":2,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9494,"is_data_producer":true,"deposit_databanks":{"ClinicalTrials.gov":["NCT05181657"]},"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":666151,"name":"Daniela Abramovitz","orcid":"0000-0002-2969-7193","position":1,"is_corresponding":false},{"id":516177,"name":"Alicia Vera","orcid":"0000-0002-8708-8169","position":2,"is_corresponding":false},{"id":1042491,"name":"Tara Stamos-Buesig","orcid":null,"position":3,"is_corresponding":false},{"id":667125,"name":"Carlos F. Vera","orcid":null,"position":4,"is_corresponding":false},{"id":666152,"name":"Irina Artamónova","orcid":"0000-0003-4584-4832","position":5,"is_corresponding":false},{"id":1090898,"name":"Jenna Logan","orcid":null,"position":6,"is_corresponding":false},{"id":404096,"name":"Thomas L. Patterson","orcid":"0000-0003-2311-6164","position":7,"is_corresponding":false},{"id":823544,"name":"Argentina E. Servin","orcid":"0000-0001-5523-7767","position":8,"is_corresponding":false},{"id":270180,"name":"Angela R. Bazzi","orcid":"0000-0001-6828-1919","position":9,"is_corresponding":false},{"id":301815,"name":"Steffanie A. Strathdee","orcid":"0000-0002-7724-691X","position":0,"is_corresponding":true}],"reference_count":42,"raw_metadata":null,"created_at":"2026-07-19T01:12:06.040073Z","pmid":"37547856","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}