{"doi":"10.1093/ofid/ofad002","title":"Efficacy of a Primary Care-Based Mobile Application to Increase Hepatitis C Screening Among Asian Americans: A Secondary Analysis of a Randomized Clinical Trial","abstract":"Abstract Background Hepatitis C virus (HCV) screening remains suboptimal. We assessed the efficacy of a mobile application and provider alert in enhancing HCV screening among Asian Americans. Methods A secondary analysis of a cluster-randomized clinical trial was performed during the birth cohort screening era to assess the efficacy of a Hepatitis App (intervention), a multilingual mobile application delivering interactive video education on viral hepatitis and creating a Provider Alert printout, at primary care clinics within 2 healthcare systems in San Francisco from 2015 to 2017. A comparison group received usual care and a similar intervention on nutrition and physical activity. The outcome was electronic health record (EHR) documentation of HCV screening along with patient-provider communication about testing and test ordering. Results Four hundred fifty-two participants (mean age 57 years, 36% male, 80% foreign-born) were randomized by provider clusters to the intervention (n = 270) or comparison groups (n = 182). At 3-month follow up, the intervention group was more likely than the comparison group to be aware of HCV (75% vs 59%, P = .006), to discuss HCV testing with their providers (63% vs 13%, P < .001), to have HCV testing ordered (39% vs 10%, P < .001), and to have EHR-verified HCV testing (30% vs 6%, P< .001). Within the intervention group, being born between 1945 and 1965 (odds ratio, 3.15; 95% confidence interval, 1.35–7.32) was associated with increased HCV testing. Conclusions The Hepatitis App delivered in primary care settings was effective in increasing HCV screening in a socioeconomically diverse Asian American cohort. This highlights the importance of mobile technology as a patient-centered strategy to address gaps in HCV care.","journal":"Open Forum Infectious Diseases","year":2023,"id":352227,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.948,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":339257,"name":"Nicole J. Kim","orcid":"0000-0003-2348-0580","position":1,"is_corresponding":false},{"id":341376,"name":"Janice Y. Tsoh","orcid":"0000-0003-0989-7187","position":2,"is_corresponding":false},{"id":916571,"name":"Judith M. E. Walsh","orcid":"0000-0002-0148-3169","position":3,"is_corresponding":false},{"id":916992,"name":"Lee Goldman","orcid":null,"position":4,"is_corresponding":false},{"id":631337,"name":"Helen Park","orcid":null,"position":5,"is_corresponding":false},{"id":1098183,"name":"Ivy Lau","orcid":null,"position":6,"is_corresponding":false},{"id":916572,"name":"Ching Wong","orcid":"0000-0001-7375-8849","position":7,"is_corresponding":false},{"id":1097754,"name":"Ginny Gildengorin","orcid":"0009-0003-1165-0076","position":8,"is_corresponding":false},{"id":107673,"name":"Tung T. Nguyen","orcid":"0000-0001-9897-6551","position":9,"is_corresponding":false},{"id":336587,"name":"Mandana Khalili","orcid":"0000-0001-9178-9139","position":0,"is_corresponding":true}],"reference_count":44,"raw_metadata":null,"created_at":"2026-07-19T01:12:50.107998Z","pmid":"36726551","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}