{"doi":"10.1093/jpids/piac010","title":"Pediatric SARS-CoV-2 Seroprevalence in Arkansas Over the First Year of the COVID-19 Pandemic","abstract":"BACKGROUND: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) seroprevalence studies largely focus on adults, but little is known about spread in children. We determined SARS-CoV-2 seroprevalence in children and adolescents from Arkansas over the first year of the coronavirus disease of 2019 (COVID-19) pandemic. METHODS: We tested remnant serum samples from children ages 1-18 years who visited Arkansas hospitals or clinics for non-COVID-19-related reasons from April 2020 through April 2021 for SARS-CoV-2 antibodies. We used univariable and multivariable regression models to determine the association between seropositivity and participant characteristics. RESULTS: Among 2357 participants, seroprevalence rose from 7.9% in April/May 2020 (95% CI, 4.9-10.9) to 25.0% in April 2021 (95% CI, 21.5-28.5). Hispanic and black children had a higher association with antibody positivity than non-Hispanic and white children, respectively, in multiple sampling periods. CONCLUSIONS: By spring 2021, most children in Arkansas were not infected with SARS-CoV-2. With the emergence of SARS-CoV-2 variants, recognition of long-term effects of COVID-19, and the lack of an authorized pediatric SARS-CoV-2 vaccine at the time, these results highlight the importance of including children in SARS-CoV-2 public health, clinical care, and research strategies.","journal":"Journal of the Pediatric Infectious Diseases Society","year":2022,"id":249200,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":28,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7803,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":456268,"name":"Joshua L. Kennedy","orcid":"0000-0002-1919-9051","position":1,"is_corresponding":false},{"id":356109,"name":"Jessica Snowden","orcid":"0000-0002-0715-151X","position":2,"is_corresponding":false},{"id":378080,"name":"Shana M. Owens","orcid":"0000-0002-2668-9868","position":3,"is_corresponding":false},{"id":889906,"name":"Marianne Kouassi","orcid":null,"position":4,"is_corresponding":false},{"id":889907,"name":"Ryan Mann","orcid":null,"position":5,"is_corresponding":false},{"id":889908,"name":"Amairani Paredes","orcid":null,"position":6,"is_corresponding":false},{"id":889909,"name":"Claire Putt","orcid":null,"position":7,"is_corresponding":false},{"id":342566,"name":"Laura P. James","orcid":"0000-0002-4266-3924","position":8,"is_corresponding":false},{"id":580268,"name":"Jing Jin","orcid":"0000-0003-1771-9938","position":9,"is_corresponding":false},{"id":889342,"name":"Ruofei Du","orcid":"0000-0002-0143-5343","position":10,"is_corresponding":false},{"id":537960,"name":"Catherine Kirkpatrick","orcid":"0009-0000-4955-2410","position":11,"is_corresponding":false},{"id":889343,"name":"Zeel Modi","orcid":"0000-0002-2529-9796","position":12,"is_corresponding":false},{"id":889910,"name":"Katherine Caid","orcid":null,"position":13,"is_corresponding":false},{"id":762129,"name":"Sean G. Young","orcid":"0000-0002-0054-0627","position":14,"is_corresponding":false},{"id":722293,"name":"Namvar Zohoori","orcid":"0000-0003-3990-8799","position":15,"is_corresponding":false},{"id":413081,"name":"Atul Kothari","orcid":"0000-0002-3236-3864","position":16,"is_corresponding":false},{"id":530593,"name":"Bobby L. Boyanton","orcid":"0000-0002-5665-7357","position":17,"is_corresponding":false},{"id":573923,"name":"J. Craig Forrest","orcid":"0000-0002-6695-0936","position":18,"is_corresponding":false},{"id":623326,"name":"Karl W. Boehme","orcid":"0000-0003-2691-9763","position":0,"is_corresponding":true}],"reference_count":47,"raw_metadata":null,"created_at":"2026-07-19T00:24:19.356023Z","pmid":"35294550","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}