{"doi":"10.1093/jncics/pkae029","title":"Unaffordable housing and cancer: novel insights into a complex question","abstract":"Recently, the US economy has been greatly affected by rising costs and low inventory in the housing and rental markets (1).Although there are many known consequences of higher out-ofpocket housing costs, including overcrowding and homelessness, little is known about how housing affordability may be affecting our national cancer burden.In this issue of the Journal, Lawrence et al. (2) tackle this question by investigating the relationship between unaffordable housing and premature death from cancer.In an ecological analysis, the authors model the relationship between quintiles of the severe housing cost burden index (defined as the percentage of households that spend 50% or more of their household income on housing) and age-adjusted countylevel mortality, with adjustment by county racial and ethnic composition, poverty, urbanicity, and median rent.Their results indicate that compared with counties with lower levels of unaffordable housing, counties with higher levels of unaffordable housing have slightly elevated rates of premature mortality from cancer.These results seem to be driven primarily by premature mortality from lung cancer.For colorectal cancer and female breast cancer, unaffordable housing does not seem to be associated with county-level rates of premature cancer mortality.For pancreatic and prostate cancers, premature mortality is generally higher in counties with lower housing cost burden.For liver cancer, there is an apparent inverse association: As the rate of unaffordable housing increases, the rate of premature mortality decreases such that counties with the highest housing cost burden have the lowest levels of premature mortality.Lawrence et al.'s findings contribute to a broader body of research on cancer and housing security.Housing security, which encompasses cost burden, lack of access to stable housing, housing discrimination, frequent moves, and homelessness, is a recognized social determinant of health (3), and adverse circumstances related to housing security are demonstrated contributors to disparities in cancer outcomes.Recently, Fan et al. reviewed 31 studies on housing insecurity and cancer care, highlighting the impact of housing security on cancer disparities and","journal":"JNCI Cancer Spectrum","year":2024,"id":497347,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9536,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":772586,"name":"Roch A. Nianogo","orcid":"0000-0001-5932-6169","position":1,"is_corresponding":false},{"id":1077990,"name":"Tammy Leonard","orcid":"0000-0002-8621-9358","position":2,"is_corresponding":false},{"id":462065,"name":"Caroline A. Thompson","orcid":"0000-0001-9990-9756","position":0,"is_corresponding":true}],"reference_count":27,"raw_metadata":null,"created_at":"2026-07-19T02:09:30.779495Z","pmid":"38708930","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}