{"doi":"10.1093/jncics/pkad007","title":"Prospective associations between accelerometry-derived physical activity and sedentary behaviors and mortality among cancer survivors","abstract":"BACKGROUND: Survival benefits of self-reported recreational physical activity (PA) during cancer survivorship are well-documented in common cancer types, yet there are limited data on the associations between accelerometer-derived PA of all domains, sedentary behavior, and mortality in large, diverse cohorts of cancer survivors. METHODS: Participants included adults who reported a cancer diagnosis in the National Health and Nutrition Examination Survey and wore an accelerometer for up to 7 days in 2003-2006. Participants were followed for subsequent mortality through 2015. We examined the association of light PA, moderate to vigorous PA, total PA, and sedentary behavior, with all-cause mortality. Cox proportional hazards models estimated hazard ratios (HRs) and 95% confidence intervals (CIs), adjusting for demographics and health indicators. RESULTS: A total of 480 participants (mean age of 68.8 years [SD = 12.4] at the time of National Health and Nutrition Examination Survey assessment) reported a history of cancer. A total of 215 deaths occurred over the follow-up period. For every 1-h/d increase in light PA and moderate to vigorous PA (MVPA), cancer survivors had 49% (HR = 0.51, 95% CI = 0.34 to 0.76) and 37% (HR = 0.63 , 95% CI = 0.40 to 0.99) lower hazards of all-cause mortality, respectively. Total PA demonstrated similar associations with statistically significantly lower hazards of death for each additional hour per day (HR = 0.68, 95% CI = 0.54 to 0.85), as did every metabolic equivalents of task-hour per day increase in total PA estimations of energy expenditure (HR = 0.88, 95% CI = 0.82 to 0.95). Conversely, more sedentary time (1 h/d) was not associated with statistically significantly higher hazards (HR = 1.08, 95% CI = 0.94 to 1.23). CONCLUSIONS: These findings reinforce the current recommendations for cancer survivors to be physically active and underscore the continued need for widespread PA promotion for long-term survival in older cancer survivors.","journal":"JNCI Cancer Spectrum","year":2023,"id":339317,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":16,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.78,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":318427,"name":"Pedro F. Saint‐Maurice","orcid":"0000-0002-8752-2340","position":1,"is_corresponding":false},{"id":502908,"name":"Fei Wan","orcid":"0000-0002-8311-5553","position":2,"is_corresponding":false},{"id":327140,"name":"Lindsay L. Peterson","orcid":"0000-0002-5012-7347","position":3,"is_corresponding":false},{"id":313804,"name":"Yikyung Park","orcid":"0000-0002-6281-489X","position":4,"is_corresponding":false},{"id":261915,"name":"Yin Cao","orcid":"0000-0001-9835-7662","position":5,"is_corresponding":false},{"id":436248,"name":"Ryan P. Duncan","orcid":"0000-0003-1725-2872","position":6,"is_corresponding":false},{"id":16808,"name":"Richard P. Troiano","orcid":"0000-0002-6807-989X","position":7,"is_corresponding":false},{"id":231465,"name":"Charles E. Matthews","orcid":"0000-0001-8037-3103","position":8,"is_corresponding":false},{"id":318425,"name":"Elizabeth A. Salerno","orcid":"0000-0001-5152-3168","position":0,"is_corresponding":true}],"reference_count":55,"raw_metadata":null,"created_at":"2026-07-19T01:10:45.048445Z","pmid":"36786414","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}