{"doi":"10.1093/jamia/ocae291","title":"Using human factors methods to mitigate bias in artificial intelligence-based clinical decision support","abstract":"OBJECTIVES: To highlight the often overlooked role of user interface (UI) design in mitigating bias in artificial intelligence (AI)-based clinical decision support (CDS). MATERIALS AND METHODS: This perspective paper discusses the interdependency between AI-based algorithm development and UI design and proposes strategies for increasing the safety and efficacy of CDS. RESULTS: The role of design in biasing user behavior is well documented in behavioral economics and other disciplines. We offer an example of how UI designs play a role in how bias manifests in our machine learning-based CDS development. DISCUSSION: Much discussion on bias in AI revolves around data quality and algorithm design; less attention is given to how UI design can exacerbate or mitigate limitations of AI-based applications. CONCLUSION: This work highlights important considerations including the role of UI design in reinforcing/mitigating bias, human factors methods for identifying issues before an application is released, and risk communication strategies.","journal":"Journal of the American Medical Informatics Association","year":2024,"id":455048,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9648,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":402031,"name":"Julie Diiulio","orcid":"0000-0002-5791-0705","position":1,"is_corresponding":false},{"id":316903,"name":"Debbie L. Wilson","orcid":"0000-0002-1640-5497","position":2,"is_corresponding":false},{"id":428173,"name":"Khoa A. Nguyen","orcid":"0000-0002-0096-0293","position":3,"is_corresponding":false},{"id":285594,"name":"Christopher A. Harle","orcid":"0000-0002-4803-3632","position":4,"is_corresponding":false},{"id":284381,"name":"Walid F. Gellad","orcid":"0000-0002-6992-5197","position":5,"is_corresponding":false},{"id":491952,"name":"Wei‐Hsuan Lo‐Ciganic","orcid":"0000-0001-6590-4770","position":6,"is_corresponding":false},{"id":402032,"name":"Laura G. Militello","orcid":"0000-0001-8445-5640","position":0,"is_corresponding":true}],"reference_count":31,"raw_metadata":null,"created_at":"2026-07-19T02:03:17.458329Z","pmid":"39569464","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}