{"doi":"10.1093/jamia/ocae261","title":"Efficacy of the mLab App: a randomized clinical trial for increasing HIV testing uptake using mobile technology","abstract":"OBJECTIVE: To determine the efficacy of the mLab App, a mobile-delivered HIV prevention intervention to increase HIV self-testing in MSM and TGW. MATERIALS AND METHODS: This was a randomized (2:2:1) clinical trial of the efficacy the mLab App as compared to standard of care vs mailed home HIV test arm among 525 MSM and TGW aged 18-29 years to increase HIV testing. RESULTS: The mLab App arm participants demonstrated an increase from 35.1% reporting HIV testing in the prior 6 months compared to 88.5% at 6 months. In contrast, 28.8% of control participants reported an HIV test at baseline, which only increased to 65.1% at 6 months. In a generalized linear mixed model estimating this change and controlling for multiple observations of participants, this equated to control participants reporting a 61.2% smaller increase in HIV testing relative to mLab participants (P = .001) at 6 months. This difference was maintained at 12 months with control participants reporting an 82.6% smaller increase relative to mLab App participants (P < .001) from baseline to 12 months. DISCUSSION AND CONCLUSION: Findings suggest that the mLab App is well-supported, evidence-based, behavioral risk-reduction intervention for increasing HIV testing rates as compared to the standard of care, suggesting that this may be a useful behavioral risk-reduction intervention for increasing HIV testing among young MSM. TRIAL REGISTRATION: This trial was registered with Clinicaltrials.gov NCT03803683.","journal":"Journal of the American Medical Informatics Association","year":2024,"id":443689,"datarank":0.337545512323081,"base_score":2.1972245773362196,"endowment":2.1972245773362196,"self_citation_contribution":0.32958368660043297,"citation_network_contribution":0.00796182572264802,"self_endowment_contribution":0.32958368660043297,"citer_contribution":0.00796182572264802,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":4,"citers_with_citation_signal":1,"citers_with_endowment":1,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.945,"is_data_producer":true,"deposit_databanks":{"ClinicalTrials.gov":["NCT03803683"]},"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":727670,"name":"Thomas Scherr","orcid":"0000-0002-7077-535X","position":1,"is_corresponding":false},{"id":387679,"name":"Lisa M. Kuhns","orcid":"0000-0001-8294-7801","position":2,"is_corresponding":false},{"id":516183,"name":"Patrick Janulis","orcid":"0000-0001-7214-2612","position":3,"is_corresponding":false},{"id":371329,"name":"Haomiao Jia","orcid":"0000-0002-1391-8190","position":4,"is_corresponding":false},{"id":728131,"name":"Olivia R. Wood","orcid":null,"position":5,"is_corresponding":false},{"id":1258870,"name":"Michael Almodovar","orcid":null,"position":6,"is_corresponding":false},{"id":294571,"name":"Robert Garofalo","orcid":"0000-0001-9513-9416","position":7,"is_corresponding":false},{"id":371331,"name":"Rebecca Schnall","orcid":"0000-0003-2184-4045","position":0,"is_corresponding":true}],"reference_count":51,"raw_metadata":null,"created_at":"2026-07-19T02:01:29.001453Z","pmid":"39560363","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}