{"doi":"10.1093/jamia/ocae093","title":"Development of a multimodal geomarker pipeline to assess the impact of social, economic, and environmental factors on pediatric health outcomes","abstract":"OBJECTIVES: We sought to create a computational pipeline for attaching geomarkers, contextual or geographic measures that influence or predict health, to electronic health records at scale, including developing a tool for matching addresses to parcels to assess the impact of housing characteristics on pediatric health. MATERIALS AND METHODS: We created a geomarker pipeline to link residential addresses from hospital admissions at Cincinnati Children's Hospital Medical Center (CCHMC) between July 2016 and June 2022 to place-based data. Linkage methods included by date of admission, geocoding to census tract, street range geocoding, and probabilistic address matching. We assessed 4 methods for probabilistic address matching. RESULTS: We characterized 124 244 hospitalizations experienced by 69 842 children admitted to CCHMC. Of the 55 684 hospitalizations with residential addresses in Hamilton County, Ohio, all were matched to 7 temporal geomarkers, 97% were matched to 79 census tract-level geomarkers and 13 point-level geomarkers, and 75% were matched to 16 parcel-level geomarkers. Parcel-level geomarkers were linked using our exact address matching tool developed using the best-performing linkage method. DISCUSSION: Our multimodal geomarker pipeline provides a reproducible framework for attaching place-based data to health data while maintaining data privacy. This framework can be applied to other populations and in other regions. We also created a tool for address matching that democratizes parcel-level data to advance precision population health efforts. CONCLUSION: We created an open framework for multimodal geomarker assessment by harmonizing and linking a set of over 100 geomarkers to hospitalization data, enabling assessment of links between geomarkers and hospital admissions.","journal":"Journal of the American Medical Informatics Association","year":2024,"id":444641,"datarank":0.31191623125197543,"base_score":2.0794415416798357,"endowment":2.0794415416798357,"self_citation_contribution":0.31191623125197543,"citation_network_contribution":0.0,"self_endowment_contribution":0.31191623125197543,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7075,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":24731,"name":"Qing Duan","orcid":"0000-0003-4467-7024","position":1,"is_corresponding":false},{"id":1260108,"name":"Stuart Taylor","orcid":"0000-0002-4395-3720","position":2,"is_corresponding":false},{"id":1260109,"name":"Sarah E. Ray","orcid":"0000-0002-5775-8344","position":3,"is_corresponding":false},{"id":1029767,"name":"Alexandra M.S. Corley","orcid":"0000-0002-5648-4396","position":4,"is_corresponding":false},{"id":1260544,"name":"Joseph Michael","orcid":null,"position":5,"is_corresponding":false},{"id":1260545,"name":"R. N. Gillette","orcid":null,"position":6,"is_corresponding":false},{"id":1260110,"name":"Ndidi Unaka","orcid":"0000-0003-4558-9931","position":7,"is_corresponding":false},{"id":1059619,"name":"David Hartley","orcid":"0000-0003-2589-2538","position":8,"is_corresponding":false},{"id":317864,"name":"Andrew F. Beck","orcid":"0000-0002-4262-663X","position":9,"is_corresponding":false},{"id":354124,"name":"Cole Brokamp","orcid":"0000-0002-0289-3151","position":10,"is_corresponding":false},{"id":1251037,"name":"Chidiogo Anyigbo","orcid":"0000-0002-2897-1445","position":11,"is_corresponding":false},{"id":372516,"name":"Lori E. Crosby","orcid":"0000-0001-6656-7745","position":12,"is_corresponding":false},{"id":1260546,"name":"Magdely Diaz de Leon","orcid":null,"position":13,"is_corresponding":false},{"id":1260111,"name":"John Egbo","orcid":"0009-0004-5465-1455","position":14,"is_corresponding":false},{"id":1260547,"name":"Ben Foley","orcid":null,"position":15,"is_corresponding":false},{"id":1260548,"name":"Adrienne W. Henize","orcid":null,"position":16,"is_corresponding":false},{"id":1260112,"name":"Margaret Jones","orcid":"0000-0002-7450-8195","position":17,"is_corresponding":false},{"id":1255684,"name":"Nana‐Hawa Yayah Jones","orcid":"0000-0002-9988-6686","position":18,"is_corresponding":false},{"id":704674,"name":"Robert S. Kahn","orcid":"0000-0002-5058-162X","position":19,"is_corresponding":false},{"id":1260549,"name":"Landon Krantz","orcid":null,"position":20,"is_corresponding":false},{"id":1260113,"name":"Lauren Lipps","orcid":"0000-0003-3133-0021","position":21,"is_corresponding":false},{"id":1260550,"name":"Alexandra Power-Hayes","orcid":null,"position":22,"is_corresponding":false},{"id":361273,"name":"Charles T. Quinn","orcid":"0000-0002-2372-2175","position":23,"is_corresponding":false},{"id":1260551,"name":"Elizabeth Quinonez","orcid":null,"position":24,"is_corresponding":false},{"id":662033,"name":"Carley Riley","orcid":"0000-0002-3306-8904","position":25,"is_corresponding":false},{"id":1260114,"name":"Laura F. Sandoval","orcid":"0000-0001-5553-7452","position":26,"is_corresponding":false},{"id":437466,"name":"Lisa M. Shook","orcid":"0000-0002-9860-5467","position":27,"is_corresponding":false},{"id":1260552,"name":"Jeffrey Steller","orcid":null,"position":28,"is_corresponding":false},{"id":1260107,"name":"Erika Rasnick Manning","orcid":"0000-0002-7150-5845","position":0,"is_corresponding":true}],"reference_count":26,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T02:01:37.886033Z","pmid":"38733117","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}