{"doi":"10.1093/infdis/jiae181","title":"Serological Evidence of Mpox Virus Infection During Peak Mpox Transmission in New York City, July to August 2022","abstract":"BACKGROUND: The extent to which infections may have been undetected in an epicenter of the 2022 mpox outbreak is unknown. METHODS: A serosurvey (July and August 2022) assessed the seroprevalence and correlates of mpox infection among a diverse sample of asymptomatic patients with no prior mpox diagnoses and no known histories of smallpox or mpox vaccination. We present seropositivity stratified by participant characteristics collected via survey. RESULTS: Two-thirds of 419 participants were cismen (281 of 419), of whom 59.1% (166 of 281) reported sex with men (MSM). The sample also included 109 ciswomen and 28 transgender/gender nonconforming/nonbinary individuals. Overall seroprevalence was 6.4% (95% confidence interval [CI], 4.1%-8.8%); 3.7% among ciswomen (95% CI, 1.0%-9.1%), 7.0% among cismen with only ciswomen partners (95% CI, 2.0%-11.9%), and 7.8% among MSM (95% CI, 3.7%-11.9%). There was little variation in seroprevalence by race/ethnicity, age group, HIV status, or number of recent sex partners. No participants who reported close contact with mpox cases were seropositive. Among participants without recent mpox-like symptoms, 6.3% were seropositive (95% CI, 3.6%-9.0%). CONCLUSIONS: Approximately 1 in 15 vaccine-naive people in our study had antibodies to mpox during the height of the NYC outbreak, indicating the presence of asymptomatic infections that could contribute to ongoing transmission.","journal":"The Journal of Infectious Diseases","year":2024,"id":438351,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":10,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9448,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":607779,"name":"Michael B. Townsend","orcid":"0000-0002-0354-7437","position":1,"is_corresponding":false},{"id":1100647,"name":"Erik Kopping","orcid":"0000-0002-0367-1251","position":2,"is_corresponding":false},{"id":791155,"name":"Jennifer Tang","orcid":"0000-0002-4160-1713","position":3,"is_corresponding":false},{"id":1248543,"name":"Terese Navarra","orcid":null,"position":4,"is_corresponding":false},{"id":337022,"name":"Lalita Priyamvada","orcid":"0000-0002-0479-0164","position":5,"is_corresponding":false},{"id":1248159,"name":"William Carson","orcid":"0000-0001-7188-8674","position":6,"is_corresponding":false},{"id":1248544,"name":"S Satheshkumar Panayampalli","orcid":null,"position":7,"is_corresponding":false},{"id":1221579,"name":"Randal C. Fowler","orcid":"0000-0002-6703-0488","position":8,"is_corresponding":false},{"id":965227,"name":"Nang Thu Thu Kyaw","orcid":"0000-0002-4849-579X","position":9,"is_corresponding":false},{"id":637880,"name":"Scott Hughes","orcid":"0000-0001-8882-2946","position":10,"is_corresponding":false},{"id":976239,"name":"Kelly Jamison","orcid":null,"position":11,"is_corresponding":false},{"id":461858,"name":"Preeti Pathela","orcid":"0000-0001-9745-6079","position":0,"is_corresponding":true}],"reference_count":17,"raw_metadata":null,"created_at":"2026-07-19T02:00:38.888629Z","pmid":"38736232","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}