{"doi":"10.1093/infdis/jiac223","title":"Control of Epstein-Barr Virus (EBV) in the Oral Cavity Is Associated With Persistence of Oral Human Papillomavirus (HPV)16/18 Among Men From the HPV Infection in Men Study","abstract":"BACKGROUND: Human papillomavirus (HPV)-related oropharyngeal cancer (OPC) incidence is increasing among men. Biomarkers that can identify oral HPV16/18 infections likely to persist, the obligate precursor for HPV-OPC, are needed. METHODS: We assessed the association between oral Epstein-Barr virus (EBV) and oral HPV16/18 persistence among 63 men in the HPV Infection in Men Study who tested positive for HPV16/18 at the baseline visit. Control of oral coinfections, including EBV, could serve as a biomarker of immune competence and the ability to control oral HPV. RESULTS: Detection of oral EBV was significantly associated with oral HPV16/18 ≥12-month persistence. CONCLUSIONS: Detection of oral EBV deserves evaluation as a biomarker for oral HPV persistence and HPV-related OPC.","journal":"The Journal of Infectious Diseases","year":2022,"id":282350,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.964,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":390461,"name":"Anna R. Giuliano","orcid":"0000-0002-5440-8859","position":1,"is_corresponding":false},{"id":407870,"name":"Bradley Sirak","orcid":null,"position":2,"is_corresponding":false},{"id":406249,"name":"Martha Abrahamsen","orcid":"0000-0001-7252-9446","position":3,"is_corresponding":false},{"id":406251,"name":"Eduardo Lazcano‐Ponce","orcid":"0000-0003-1259-6369","position":4,"is_corresponding":false},{"id":406250,"name":"Luisa L. Villa","orcid":"0000-0003-4074-2335","position":5,"is_corresponding":false},{"id":454717,"name":"Anna E. Coghill","orcid":"0000-0001-7142-7499","position":6,"is_corresponding":false},{"id":520598,"name":"Brittney L. Dickey","orcid":"0000-0002-4268-6149","position":0,"is_corresponding":true}],"reference_count":16,"raw_metadata":null,"created_at":"2026-07-19T00:29:15.734856Z","pmid":"35679351","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}