{"doi":"10.1093/infdis/jiac004","title":"Natural History of Incident and Persistent Cutaneous Human Papillomavirus and Human Polyomavirus Infections","abstract":"BACKGROUND: Cutaneous human papillomaviruses (cuHPV) and polyomaviruses (HPyV) have been implicated in skin cancers; however, interpretation of findings across studies is complicated by limited understanding of the natural history of these infections across normal tissue types. METHODS: In total, 675 eyebrow hair (EBH) and skin swab (SSW) samples were collected from 71 skin cancer screening patients every 6 months over 2 years and measured for presence of β-HPV, γ-HPV, and HPyV. Incidence, persistence, and clearance of cuHPV/HPyV were estimated, and risk factors associated with infection were examined. RESULTS: Prevalence, incidence, and persistence of β-HPV, γ-HPV, and HPyV were consistently higher in SSW than in EBH, with types 5, 24, 49, 76 and Merkel cell polyomavirus (MCPyV) having incidence rates greater than 20 per 1000 person-months. Prevalent γ-HPV EBH infections persisted more often in women (P = .024), incident β-HPV EBH infections persisted less often among individuals with history of blistering sunburn (P = .019), and prevalent MCPyV SSW infections persisted more often in those with a history of skin cancer (P = .033). CONCLUSIONS: Incidence and persistence of cuHPV/HPyV were observed in SSW and EBH; however, none of the risk factors examined were commonly associated with cuHPV/HPyV infections across normal tissue types.","journal":"The Journal of Infectious Diseases","year":2022,"id":285966,"datarank":0.2606184150479014,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.019202728182786323,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.019202728182786323,"corpus_percentile":41.06908021969521,"corpus_rank":7619,"citation_count":4,"citer_count":3,"citers_with_citation_signal":2,"citers_with_endowment":2,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.6299,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":447923,"name":"Yayi Zhao","orcid":"0000-0003-0806-823X","position":1,"is_corresponding":false},{"id":447925,"name":"Neil A. Fenske","orcid":"0000-0002-0057-2434","position":2,"is_corresponding":false},{"id":431072,"name":"Basil S. Cherpelis","orcid":null,"position":3,"is_corresponding":false},{"id":341887,"name":"Jane L. Messina","orcid":"0000-0002-0332-0224","position":4,"is_corresponding":false},{"id":390461,"name":"Anna R. Giuliano","orcid":"0000-0002-5440-8859","position":5,"is_corresponding":false},{"id":403074,"name":"Vernon K. Sondak","orcid":"0000-0003-1090-484X","position":6,"is_corresponding":false},{"id":318016,"name":"Michael J. Schell","orcid":"0000-0003-4594-6601","position":7,"is_corresponding":false},{"id":447926,"name":"Sandrine McKay‐Chopin","orcid":"0000-0002-4694-0415","position":8,"is_corresponding":false},{"id":447927,"name":"Tarik Gheit","orcid":"0000-0001-7088-337X","position":9,"is_corresponding":false},{"id":390102,"name":"Tim Waterboer","orcid":"0000-0002-0616-6963","position":10,"is_corresponding":false},{"id":447928,"name":"Massimo Tommasino","orcid":"0000-0002-0890-8596","position":11,"is_corresponding":false},{"id":414057,"name":"Dana E. Rollison","orcid":"0000-0002-3171-8045","position":12,"is_corresponding":false},{"id":447924,"name":"Rossybelle P. Amorrortu","orcid":"0000-0001-6851-0179","position":0,"is_corresponding":true}],"reference_count":42,"raw_metadata":null,"created_at":"2026-07-19T00:29:48.841035Z","pmid":"35022780","pmcid":"PMC9518839","fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}