{"doi":"10.1093/ibd/izad177","title":"Extensive Colitis and Smoking Are Associated With Postoperative Complications Within 30 Days of Ileal Pouch–Anal Anastomosis","abstract":"BACKGROUND: Our understanding of outcomes after proctocolectomy with ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) is largely based on analyses of selected populations. We created a state-level registry to evaluate the epidemiology of IPAA surgery and pouch-related outcomes across the major healthcare systems performing these surgeries in our state. METHODS: We created a retrospective cohort of all patients undergoing restorative proctocolectomy with IPAA for UC at 1 of 4 centers between January 1, 2018, and December 31, 2020. The primary outcomes of this study were the rate of complications and all-cause readmissions within the first 30 days of the final stage of IPAA surgery. RESULTS: During the study period, 177 patients underwent IPAA surgery with 66 (37%) experiencing a complication within 30 days. After adjusting for the number of stages in IPAA surgery, patients with extensive UC (odds ratio, 3.61; 95% confidence interval, 1.39-9.33) and current or former smokers (odds ratio, 2.98; 95% confidence interval, 1.38-6.45) were more likely to experience a complication. Among all patients, 57 (32%) required readmission within 30 days. The most common reasons for readmission were ileus/small bowel obstruction (22%), peripouch abscess (19%), and dehydration (16%). CONCLUSION: In this first state-level examination of the epidemiology of IPAA for UC, we demonstrated that the complication rate after IPAA for UC was 37%, with one-third of patients being readmitted within 30 days. Extensive disease at the time of colectomy appears to be an indicator of more severe disease and may portend a worse prognosis after IPAA.","journal":"Inflammatory Bowel Diseases","year":2023,"id":386613,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7773,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":730830,"name":"Scott Esckilsen","orcid":null,"position":1,"is_corresponding":false},{"id":1155504,"name":"Jean Ashburn","orcid":null,"position":2,"is_corresponding":false},{"id":1155505,"name":"Amy Barto","orcid":null,"position":3,"is_corresponding":false},{"id":1062307,"name":"Richard S. Bloomfeld","orcid":null,"position":4,"is_corresponding":false},{"id":1155506,"name":"Ashley Cairns","orcid":null,"position":5,"is_corresponding":false},{"id":454306,"name":"Kurren Mehta","orcid":"0000-0003-1636-7213","position":6,"is_corresponding":false},{"id":1155142,"name":"Pooja Patel","orcid":"0000-0001-9834-006X","position":7,"is_corresponding":false},{"id":1155507,"name":"Jennifer Dziwis","orcid":null,"position":8,"is_corresponding":false},{"id":1155143,"name":"Michael Dunn","orcid":"0000-0002-3908-4147","position":9,"is_corresponding":false},{"id":593192,"name":"Reza Rahbar","orcid":"0000-0002-6531-5922","position":10,"is_corresponding":false},{"id":593761,"name":"Timothy S. Sadiq","orcid":null,"position":11,"is_corresponding":false},{"id":889609,"name":"John S. Hanson","orcid":"0000-0003-0235-0074","position":12,"is_corresponding":false},{"id":233525,"name":"Hans Herfarth","orcid":"0000-0003-4268-823X","position":13,"is_corresponding":false},{"id":280893,"name":"Edward L. Barnes","orcid":"0000-0001-9894-8796","position":0,"is_corresponding":true}],"reference_count":41,"raw_metadata":null,"created_at":"2026-07-19T01:18:00.717763Z","pmid":"37607334","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}