{"doi":"10.1093/ibd/izac099","title":"Long-Term Outcomes of the Excluded Rectum in Crohn’s Disease: A Multicenter International Study","abstract":"BACKGROUND: Many patients with Crohn's disease (CD) require fecal diversion. To understand the long-term outcomes, we performed a multicenter review of the experience with retained excluded rectums. METHODS: We reviewed the medical records of all CD patients between 1990 and 2014 who had undergone diversionary surgery with retention of the excluded rectum for at least 6 months and who had at least 2 years of postoperative follow-up. RESULTS: From all the CD patients in the institutions' databases, there were 197 who met all our inclusion criteria. A total of 92 (46.7%) of 197 patients ultimately underwent subsequent proctectomy, while 105 (53.3%) still had retained rectums at time of last follow-up. Among these 105 patients with retained rectums, 50 (47.6%) underwent reanastomosis, while the other 55 (52.4%) retained excluded rectums. Of these 55 patients whose rectums remained excluded, 20 (36.4%) were symptom-free, but the other 35 (63.6%) were symptomatic. Among the 50 patients who had been reconnected, 28 (56%) were symptom-free, while 22(44%) were symptomatic. From our entire cohort of 197 cases, 149 (75.6%) either ultimately lost their rectums or remained symptomatic with retained rectums, while only 28 (14.2%) of 197, and only 4 (5.9%) of 66 with initial perianal disease, were able to achieve reanastomosis without further problems. Four patients developed anorectal dysplasia or cancer. CONCLUSIONS: In this multicenter cohort of patients with CD who had fecal diversion, fewer than 15%, and only 6% with perianal disease, achieved reanastomosis without experiencing disease persistence.","journal":"Inflammatory Bowel Diseases","year":2022,"id":286287,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9532,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":240763,"name":"Clara Yzet","orcid":"0000-0001-7790-3919","position":1,"is_corresponding":false},{"id":965207,"name":"N. Nair","orcid":"0000-0002-4437-4317","position":2,"is_corresponding":false},{"id":576514,"name":"Anketse Debebe","orcid":null,"position":3,"is_corresponding":false},{"id":965598,"name":"Alexa Rendon","orcid":null,"position":4,"is_corresponding":false},{"id":109042,"name":"Jean‐Frédéric Colombel","orcid":"0000-0001-6472-249X","position":5,"is_corresponding":false},{"id":744644,"name":"Cindy Traboulsi","orcid":"0000-0001-9868-3687","position":6,"is_corresponding":false},{"id":16028,"name":"David T. Rubin","orcid":"0000-0001-5647-1723","position":7,"is_corresponding":false},{"id":965208,"name":"Annalisa Maroli","orcid":"0000-0002-7576-9629","position":8,"is_corresponding":false},{"id":965209,"name":"Elisabetta Coppola","orcid":"0000-0001-7765-8909","position":9,"is_corresponding":false},{"id":965210,"name":"Michele Carvello","orcid":"0000-0002-8650-2321","position":10,"is_corresponding":false},{"id":965599,"name":"Nadat Ben David","orcid":null,"position":11,"is_corresponding":false},{"id":965211,"name":"Francesca De Lucia","orcid":"0000-0003-2233-0871","position":12,"is_corresponding":false},{"id":965212,"name":"Matteo Sacchi","orcid":"0000-0001-8313-4909","position":13,"is_corresponding":false},{"id":240771,"name":"Silvio Danese","orcid":"0000-0001-7341-1351","position":14,"is_corresponding":false},{"id":738951,"name":"Antonino Spinelli","orcid":"0000-0002-1493-1768","position":15,"is_corresponding":false},{"id":965600,"name":"Meike M. Hirdes","orcid":null,"position":16,"is_corresponding":false},{"id":965601,"name":"Joren Ten Hove","orcid":null,"position":17,"is_corresponding":false},{"id":646090,"name":"Bas Oldenburg","orcid":"0000-0002-3962-6831","position":18,"is_corresponding":false},{"id":965602,"name":"Aurada Cholapranee","orcid":null,"position":19,"is_corresponding":false},{"id":965603,"name":"Maxine Riter","orcid":null,"position":20,"is_corresponding":false},{"id":690887,"name":"Dana J. Lukin","orcid":"0000-0003-4581-2267","position":21,"is_corresponding":false},{"id":233524,"name":"Ellen Scherl","orcid":"0000-0002-8599-4045","position":22,"is_corresponding":false},{"id":870010,"name":"Eren Esen","orcid":"0000-0002-4905-7142","position":23,"is_corresponding":false},{"id":965213,"name":"Keith Sultan","orcid":"0000-0002-7619-2024","position":24,"is_corresponding":false},{"id":345072,"name":"Jordan E. Axelrad","orcid":"0000-0003-1951-7790","position":25,"is_corresponding":false},{"id":965604,"name":"David B. Sachar","orcid":null,"position":26,"is_corresponding":false},{"id":965206,"name":"Gassan Kassim","orcid":"0000-0002-9820-3660","position":0,"is_corresponding":true}],"reference_count":21,"raw_metadata":null,"created_at":"2026-07-19T00:29:48.841035Z","pmid":"35522225","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}