{"doi":"10.1093/gerona/glae222","title":"The Cumulative Burden of Social Risk Factors and 10-Year Change in Quality of Life","abstract":"BACKGROUND: Social risk factors are linked to adverse health outcomes, but their total impact on long-term quality of life is obscure. We hypothesized that a higher burden of social risk factors is associated with greater decline in quality of life over 10 years. METHODS: We examined associations between social risk factors count and decline >5 points in (i) physical component summary, and (ii) mental component summary scores from the Short Form-12 among Black and White participants in the Reasons for Geographic and Racial Differences in Stroke study (n = 14 401). RESULTS: For physical component summary, White participants with 1 social risk factor had relative risk (RR) for decline of 1.14 [95% confidence intervals (CI): 1.07-1.12]. Those with ≥2 social risk factors had RR of 1.26 [95% CI: 1.17-1.35], after adjusting for baseline demographics, health behaviors, medical conditions, medications, and physiological variables. Black participants with 1 social risk factor had RR of 1.03 [95% CI: 0.93-1.15]. Those with ≥2 social risk factors had RR of 1.24 [95% CI: 1.13-1.36]. For mental component summary, White participants with 1 social risk factor had RR for decline of 1.19 [95% CI: 1.04-1.37]. Those with ≥2 social risk factors had RR of 1.47 [95% CI: 1.28-1.68]. Black participants with 1 social risk factor had RR of 1.18 [95% CI: 0.96-1.45]. Those with ≥2 social risk factors had RR of 1.38 [95% CI: 1.14-1.66]. CONCLUSIONS: More social risk factors increased the risk of decline of quality of life for Black and White individuals, especially impacting mental health.","journal":"The Journals of Gerontology Series A","year":2024,"id":482831,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.96,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1261521,"name":"Monika Safford","orcid":null,"position":1,"is_corresponding":false},{"id":661983,"name":"W. Marcus Lambert","orcid":"0000-0002-4592-5176","position":2,"is_corresponding":false},{"id":1323753,"name":"Joanna Bryan","orcid":null,"position":3,"is_corresponding":false},{"id":318728,"name":"Laura C. Pinheiro","orcid":"0000-0002-6920-8526","position":4,"is_corresponding":false},{"id":502595,"name":"Madeline R. Sterling","orcid":"0000-0002-9928-4407","position":5,"is_corresponding":false},{"id":687514,"name":"C. Barrett Bowling","orcid":"0000-0001-6265-8623","position":6,"is_corresponding":false},{"id":342610,"name":"Emily B. Levitan","orcid":"0000-0002-5429-3852","position":7,"is_corresponding":false},{"id":514577,"name":"Samprit Banerjee","orcid":"0000-0001-6936-0846","position":8,"is_corresponding":false},{"id":278694,"name":"Raegan W. Durant","orcid":"0000-0001-5341-3288","position":9,"is_corresponding":false},{"id":865607,"name":"Michael Kim","orcid":"0000-0003-0087-0199","position":10,"is_corresponding":false},{"id":623444,"name":"Jennifer D. Lau","orcid":"0000-0002-8362-1309","position":11,"is_corresponding":false},{"id":228353,"name":"Parag Goyal","orcid":"0000-0001-7474-3737","position":12,"is_corresponding":false},{"id":1323329,"name":"Ro-Jay Reid","orcid":"0000-0002-5279-4872","position":0,"is_corresponding":true}],"reference_count":39,"raw_metadata":null,"created_at":"2026-07-19T02:07:18.280369Z","pmid":"39749982","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}