{"doi":"10.1093/gerona/glab349","title":"Associations of Visual Function With Cognitive Performance in Community-Based Older Adults: The Eye Determinants of Cognition Study","abstract":"BACKGROUND: Given the detrimental impacts of visual and cognitive impairment separately, in older adults, understanding their coexistence could inform strategies against age-related cognitive changes. METHODS: Participants from Washington County (White) and Jackson (Black) sites of the Atherosclerosis Risk in Communities Study were recruited who differed on racial, regional, urbanicity, and community-based factors. Presenting distance visual acuity (DVA; representing vision loss due to disease or lack of eye-care), corrected DVA (representing optimal correction for refractive loss of vision), and contrast sensitivity were measured. Factor scores for global cognition, memory, executive function, and language domains were calculated for 3 visits. We quantified the associations of vision measures with change in cognitive scores, stratified by community/race, using generalized estimating equations. RESULTS: In 982 participants, mean (standard deviation [SD]) baseline age was 74 (4) years, with 37% males and 45% Jackson/Black participants. As hypothesized, after accounting for potential confounders, in the better-eye, worse presenting DVA was associated with greater 10-year decline rate in global cognition, memory, and executive function in Washington County/White participants (eg, global cognition: -0.08 SD [95% confidence interval: -0.12, -0.04]). Worse corrected DVA was associated with greater 10-year decline rate in executive function in Washington County/White participants (-0.10 SD [-0.15, -0.04]). Better contrast sensitivity was associated with lower 10-year decline rate in global cognition and executive function in Washington County/White participants (eg, global cognition: 0.10 SD [0.06,0.14]). None of these associations were confirmed in Jackson/Black participants. CONCLUSIONS: Our study supports a functional link between some vision measures and cognition in older adults, but in only 1 of the 2 communities studied.","journal":"The Journals of Gerontology Series A","year":2021,"id":199629,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":9,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.757,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":699679,"name":"Xinxing Guo","orcid":"0000-0001-5628-1225","position":1,"is_corresponding":false},{"id":342307,"name":"Pradeep Y. Ramulu","orcid":"0000-0002-9275-0401","position":2,"is_corresponding":false},{"id":699682,"name":"A. Richey Sharrett","orcid":"0000-0002-8835-7770","position":3,"is_corresponding":false},{"id":361967,"name":"Aleksandra Mihailović","orcid":"0000-0002-7550-5164","position":4,"is_corresponding":false},{"id":291486,"name":"Bonnielin K. Swenor","orcid":"0000-0002-6044-0951","position":5,"is_corresponding":false},{"id":73351,"name":"Thomas H. Mosley","orcid":"0000-0003-3343-1352","position":6,"is_corresponding":false},{"id":699681,"name":"Yanan Dong","orcid":"0000-0003-0888-4237","position":7,"is_corresponding":false},{"id":303931,"name":"Alison G. Abraham","orcid":"0000-0002-6863-0565","position":8,"is_corresponding":false},{"id":699680,"name":"Lubaina T. Arsiwala-Scheppach","orcid":"0000-0002-1428-6543","position":0,"is_corresponding":true}],"reference_count":51,"raw_metadata":null,"created_at":"2026-07-18T23:50:40.558460Z","pmid":"35089306","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}