{"doi":"10.1093/gerona/glaa137","title":"Associations of Actigraphic Sleep Parameters With Fatigability in Older Adults","abstract":"BACKGROUND: Poor sleep may increase the likelihood of fatigue, and both are common in later life. However, prior studies of the sleep-fatigue relationship used subjective measures or were conducted in clinical populations; thus, the nature of this association in healthier community-dwelling older adults remains unclear. We studied the association of actigraphic sleep parameters with perceived fatigability-fatigue in response to a standardized task-and with conventional fatigue symptoms of low energy or tiredness. METHODS: We studied 382 cognitively normal participants in the Baltimore Longitudinal Study of Aging (aged 73.1 ± 10.3 years, 53.1% women) who completed 6.7 ± 0.9 days of wrist actigraphy and a perceived fatigability assessment, including rating of perceived exertion (RPE) after a 5-minute treadmill walk or the Pittsburgh Fatigability Scale (PFS). Participants also reported non-standardized symptoms of fatigue. RESULTS: After adjustment for age, sex, race, height, weight, comorbidity index, and depressive symptoms, shorter total sleep time (TST; <6.3 hours vs intermediate TST ≥6.3 to 7.2 hours) was associated with high RPE fatigability (odds ratio [OR] = 2.56, 95% confidence interval [CI] = 1.29, 5.06, p = .007), high PFS physical (OR = 1.88, 95% CI = 1.04, 3.38, p = .035), and high mental fatigability (OR = 2.15, 95% CI = 1.02, 4.50, p = .044), whereas longer TST was also associated with high mental fatigability (OR = 2.19, 95% CI = 1.02, 4.71, p = .043). Additionally, longer wake bout length was associated with high RPE fatigability (OR = 1.53, 95% CI = 1.14, 2.07, p = .005), and greater wake after sleep onset was associated with high mental fatigability (OR = 1.14, 95% CI = 1.01, 1.28, p = .036). CONCLUSION: Among well-functioning older adults, abnormal sleep duration and sleep fragmentation are associated with greater perceived fatigability.","journal":"The Journals of Gerontology Series A","year":2020,"id":103176,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":25,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9626,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":264188,"name":"Jennifer A. Schrack","orcid":"0000-0001-9244-9267","position":1,"is_corresponding":false},{"id":381541,"name":"Jacek Urbanek","orcid":"0000-0002-1890-8899","position":2,"is_corresponding":false},{"id":409899,"name":"Amal A. Wanigatunga","orcid":"0000-0002-5763-5184","position":3,"is_corresponding":false},{"id":503931,"name":"Sarah Wanigatunga","orcid":null,"position":4,"is_corresponding":false},{"id":490122,"name":"Vadim Zipunnikov","orcid":"0000-0001-9864-2420","position":5,"is_corresponding":false},{"id":21956,"name":"Luigi Ferrucci","orcid":"0000-0002-6273-1613","position":6,"is_corresponding":false},{"id":264194,"name":"Eleanor M. Simonsick","orcid":"0000-0002-5460-3494","position":7,"is_corresponding":false},{"id":439252,"name":"Adam P. Spira","orcid":"0000-0003-1507-0995","position":8,"is_corresponding":false},{"id":329633,"name":"Alfonso J. Alfini","orcid":"0000-0002-8743-8923","position":0,"is_corresponding":true}],"reference_count":47,"raw_metadata":null,"created_at":"2026-07-18T22:42:17.920911Z","pmid":"32502253","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}