{"doi":"10.1093/ehjdh/ztag014","title":"Effectiveness of remote monitoring for patients with a high risk of cardiovascular disease: a 12-month matched cohort study in primary care","abstract":"<jats:title>Abstract</jats:title>\n                  <jats:sec>\n                    <jats:title>Aims</jats:title>\n                    <jats:p>This study aimed to evaluate the effect of remote monitoring using the Cardiovascular Risk Management (CVRM)-Box on blood pressure control, weight management, medication prescriptions, and consultation frequency in primary care patients at high risk of cardiovascular disease (CVD).</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results</jats:title>\n                    <jats:p>In this matched cohort study, patients with a &amp;gt; 5% 10-year CVD mortality risk in primary care (2020–2024) were compared to propensity score-matched controls over 12 months. The CVRM-Box included smartphone-connected devices (blood pressure monitor, weighing scale, activity tracker) linked to general practitioner electronic health records.</jats:p>\n                    <jats:p>Compared to controls, the intervention group showed modest reductions in office-measured systolic {−1.1 mmHg [95% confidence interval (CI), −3.7 to −1.5]; P = 0.39} and diastolic blood pressure [−0.04 mmHg (95% CI, −1.6 to 1.5); P = 0.96]. Sensitivity analyses yielded similar results. However, CVRM-Box assessments showed reductions in systolic [−5.5 mmHg (95% CI, −7.6 to −3.3); P &amp;lt; 0.001] and diastolic blood pressure [−3.8 mmHg (95% CI, −5.1 to −2.4); P &amp;lt; 0.001]. The intervention group also experienced greater reductions in weight [−0.9 kg (95% CI, −1.6 to −0.2); P = 0.01] and body mass index [−0.3 kg/m² (95% CI, −0.5 to −0.01); P = 0.007]. Additionally, antihypertensive medication use increased [0.12 (95% CI, 0.06 to 0.23); P = 0.04], while consultation frequency decreased (rate ratio 0.82; P = 0.002).</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion</jats:title>\n                    <jats:p>While office measurements showed no additional blood pressure reduction, CVRM-Box measurements demonstrated significant decreases. The intervention also improved target blood pressure achievement, promoted weight reduction, increased antihypertensive use, and reduced consultation frequency.</jats:p>\n                  </jats:sec>","journal":"European Heart Journal - Digital Health","year":2026,"id":614352,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1583089,"name":"Margot M Rakers","orcid":"0000-0001-8233-1150","position":1,"is_corresponding":false},{"id":1583090,"name":"Eric G Hiddink","orcid":null,"position":2,"is_corresponding":false},{"id":350960,"name":"Saskia le Cessie","orcid":"0000-0003-2154-4923","position":3,"is_corresponding":false},{"id":1583091,"name":"Just A H Eekhof","orcid":null,"position":4,"is_corresponding":false},{"id":1583092,"name":"Frank den Heijer","orcid":null,"position":5,"is_corresponding":false},{"id":1583093,"name":"Niels H Chavannes","orcid":null,"position":6,"is_corresponding":false},{"id":1583094,"name":"Hendrikus J A van Os","orcid":null,"position":7,"is_corresponding":false},{"id":1573007,"name":"Douwe E Atsma","orcid":null,"position":8,"is_corresponding":false},{"id":1583095,"name":"Tobias N Bonten","orcid":null,"position":9,"is_corresponding":false},{"id":1583088,"name":"Nicoline E van Hattem","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Effectiveness of remote monitoring for patients with a high risk of cardiovascular disease: a 12-month matched cohort study in primary care","abstract":"<jats:title>Abstract</jats:title>\n                  <jats:sec>\n                    <jats:title>Aims</jats:title>\n                    <jats:p>This study aimed to evaluate the effect of remote monitoring using the Cardiovascular Risk Management (CVRM)-Box on blood pressure control, weight management, medication prescriptions, and consultation frequency in primary care patients at high risk of cardiovascular disease (CVD).</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results</jats:title>\n                    <jats:p>In this matched cohort study, patients with a &amp;gt; 5% 10-year CVD mortality risk in primary care (2020–2024) were compared to propensity score-matched controls over 12 months. The CVRM-Box included smartphone-connected devices (blood pressure monitor, weighing scale, activity tracker) linked to general practitioner electronic health records.</jats:p>\n                    <jats:p>Compared to controls, the intervention group showed modest reductions in office-measured systolic {−1.1 mmHg [95% confidence interval (CI), −3.7 to −1.5]; P = 0.39} and diastolic blood pressure [−0.04 mmHg (95% CI, −1.6 to 1.5); P = 0.96]. Sensitivity analyses yielded similar results. However, CVRM-Box assessments showed reductions in systolic [−5.5 mmHg (95% CI, −7.6 to −3.3); P &amp;lt; 0.001] and diastolic blood pressure [−3.8 mmHg (95% CI, −5.1 to −2.4); P &amp;lt; 0.001]. The intervention group also experienced greater reductions in weight [−0.9 kg (95% CI, −1.6 to −0.2); P = 0.01] and body mass index [−0.3 kg/m² (95% CI, −0.5 to −0.01); P = 0.007]. Additionally, antihypertensive medication use increased [0.12 (95% CI, 0.06 to 0.23); P = 0.04], while consultation frequency decreased (rate ratio 0.82; P = 0.002).</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion</jats:title>\n                    <jats:p>While office measurements showed no additional blood pressure reduction, CVRM-Box measurements demonstrated significant decreases. The intervention also improved target blood pressure achievement, promoted weight reduction, increased antihypertensive use, and reduced consultation frequency.</jats:p>\n                  </jats:sec>","is_dataset_classified":null,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"41704580","pmcid":"PMC12907927","openalex_id":"https://openalex.org/W7125491152","authors":[],"funders":[{"funder_name":"IMDI","grant_id":"LSHM21009","title":null},{"funder_name":"IMDI","grant_id":"3463471-1039183-PZO","title":null}],"total_grants":2,"fwci":14.9149,"citation_percentile":0.96090467,"influential_citations":0,"citation_trend":[{"year":2026,"count":1}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://doi.org/10.1093/ehjdh/ztag014","host_type":"journal"},{"url":"https://doi.org/10.1093/ehjdh/ztag014","host_type":"publisher"},{"url":"https://academic.oup.com/ehjdh/advance-article-pdf/doi/10.1093/ehjdh/ztag014/66543822/ztag014.pdf","host_type":"publisher"},{"url":"https://academic.oup.com/ehjdh/article-pdf/7/2/ztag014/66543822/ztag014.pdf","host_type":"publisher"},{"url":"https://pubmed.ncbi.nlm.nih.gov/41704580","host_type":"repository"},{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12907927/","host_type":"repository"},{"url":"https://hdl.handle.net/1887/4296169","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC12907927","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC12907927?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Mobile Health and mHealth Applications","Blood Pressure and Hypertension Studies","Health Promotion and Cardiovascular Prevention"],"mesh_terms":[],"keywords":["Blood pressure","Primary care","Cohort","Cohort study","Intervention (counseling)","Hemodynamics","Risk stratification","Preventive Care","Blood Pressure Control","Chronic Disease Management","Remote Monitoring","Digital Health"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-02T12:42:37.583845Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}