{"doi":"10.1093/ecco-jcc/jjaa243","title":"Physician Practice Patterns in Holding Inflammatory Bowel Disease Medications due to COVID-19, in the SECURE-IBD Registry","abstract":"BACKGROUND: We aimed to describe physician practice patterns in holding or continuing IBD therapy in the setting of COVID-19 infection, using the Surveillance Epidemiology of Coronavirus Under Research Exclusion for Inflammatory Bowel Disease [SECURE-IBD] registry. METHODS: IBD medications that were stopped due to COVID-19 were recorded in the SECURE-IBD registry in addition to demographic and clinical data. We conducted descriptive analyses to understand characteristics associated with stopping IBD medications in response to active COVID-19 infection. RESULTS: Of 1499 patients, IBD medications were stopped in 518 [34.6%] patients. On bivariate and multivariable analyses, a diagnosis of ulcerative colitis or IBD-unspecified was associated with a lower odds of stopping medication compared with Crohn's disease (adjusted odds ratio [aOR] 0.6, 95% confidence interval [CI] 0.48, 0.75). When evaluating specific medications, 5-aminosalicylic acid was more likely to be continued [p <0.001] whereas anti-tumour necrosis factor therapy and immunomodulator therapy were more likely to be stopped [global p <0.001]. Other demographic and clinical characteristics did not affect prescription patterns. CONCLUSIONS: IBD medications other than immunomodulators were continued in the majority of IBD patients with COVID-19, in the international SECURE-IBD registry. Future studies are needed to understand the impact of stopping or continuing IBD medications on IBD- and COVID-19 related outcomes.","journal":"Journal of Crohn s and Colitis","year":2020,"id":83815,"datarank":0.8996719606137855,"base_score":2.4849066497880004,"endowment":2.4849066497880004,"self_citation_contribution":0.37273599746820013,"citation_network_contribution":0.5269359631455854,"self_endowment_contribution":0.37273599746820013,"citer_contribution":0.5269359631455854,"corpus_percentile":77.58954127020964,"corpus_rank":2898,"citation_count":11,"citer_count":10,"citers_with_citation_signal":9,"citers_with_endowment":9,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.8207,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":109030,"name":"Erica J. Brenner","orcid":"0000-0003-0292-3637","position":1,"is_corresponding":false},{"id":280894,"name":"Xian Zhang","orcid":"0000-0003-4079-9470","position":2,"is_corresponding":false},{"id":109042,"name":"Jean‐Frédéric Colombel","orcid":"0000-0001-6472-249X","position":3,"is_corresponding":false},{"id":109043,"name":"Michael D. Kappelman","orcid":"0000-0002-0469-6856","position":4,"is_corresponding":false},{"id":109031,"name":"Ryan C. Ungaro","orcid":"0000-0001-8687-3758","position":5,"is_corresponding":false},{"id":109032,"name":"Richard B. Gearry","orcid":"0000-0002-2298-5141","position":6,"is_corresponding":false},{"id":431468,"name":"Gilaad G Kalpan","orcid":null,"position":7,"is_corresponding":false},{"id":109034,"name":"Michele Kissous-Hunt","orcid":null,"position":8,"is_corresponding":false},{"id":49763,"name":"James D. Lewis","orcid":"0000-0003-3107-3862","position":9,"is_corresponding":false},{"id":109035,"name":"Siew C. Ng","orcid":"0000-0002-6850-4454","position":10,"is_corresponding":false},{"id":109036,"name":"Jean‐François Rahier","orcid":"0000-0002-7738-0238","position":11,"is_corresponding":false},{"id":109037,"name":"Walter Reinisch","orcid":"0000-0002-2088-091X","position":12,"is_corresponding":false},{"id":109038,"name":"Frank M. Ruemmele","orcid":"0000-0001-5571-4957","position":13,"is_corresponding":false},{"id":109039,"name":"Flávio Steinwurz","orcid":"0000-0003-1002-9766","position":14,"is_corresponding":false},{"id":109040,"name":"Fox E. Underwood","orcid":null,"position":15,"is_corresponding":false},{"id":105237,"name":"Manasi Agrawal","orcid":"0000-0003-4729-1485","position":0,"is_corresponding":true}],"reference_count":2,"raw_metadata":null,"created_at":"2026-07-18T21:54:32.422022Z","pmid":"33232456","pmcid":"PMC7717203","fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}