{"doi":"10.1093/crocol/otac030","title":"Treatment Patterns and Standardized Outcome Assessments Among Patients With Inflammatory Conditions of the Pouch in a Prospective Multicenter Registry","abstract":"Background: Much of our understanding about the natural history of pouch-related disorders has been generated from selected populations. We designed a geographically diverse, prospective registry to study the disease course among patients with 1 of 4 inflammatory conditions of the pouch. The primary objectives in this study were to demonstrate the feasibility of a prospective pouch registry and to evaluate the predominant treatment patterns for pouch-related disorders. Methods: We used standardized diagnostic criteria to prospectively enroll patients with acute pouchitis, chronic antibiotic-dependent pouchitis (CADP), chronic antibiotic refractory pouchitis (CARP), or Crohn's disease (CD) of the pouch. We obtained detailed clinical and demographic data at the time of enrollment, along with patient-reported outcome (PRO) measures. Results: < .001). Among patients with active disease at the time of enrollment, 23% with CARP and 40% with CD of the pouch were in clinical remission at 6 months after enrollment. Conclusions: In a population where most patients had refractory inflammatory conditions of the pouch, we established a framework to evaluate PROs and clinical effectiveness. This infrastructure will be valuable for long-term studies of real-world effectiveness for pouch-related disorders.","journal":"Crohn s & Colitis 360","year":2022,"id":263361,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":13,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9452,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":277906,"name":"Parakkal Deepak","orcid":"0000-0002-3436-9784","position":1,"is_corresponding":false},{"id":277913,"name":"Poonam Beniwal‐Patel","orcid":"0000-0002-2201-8100","position":2,"is_corresponding":false},{"id":210142,"name":"Laura H. Raffals","orcid":null,"position":3,"is_corresponding":false},{"id":443183,"name":"Maia Kayal","orcid":"0000-0002-9640-950X","position":4,"is_corresponding":false},{"id":235305,"name":"Marla C. Dubinsky","orcid":"0000-0003-4968-5795","position":5,"is_corresponding":false},{"id":583842,"name":"Shannon Chang","orcid":null,"position":6,"is_corresponding":false},{"id":395812,"name":"Peter Higgins","orcid":"0000-0003-1602-4341","position":7,"is_corresponding":false},{"id":920312,"name":"Jennifer I Barr","orcid":null,"position":8,"is_corresponding":false},{"id":370002,"name":"Joseph A. Galanko","orcid":"0000-0003-2304-4375","position":9,"is_corresponding":false},{"id":353598,"name":"Yue Jiang","orcid":"0000-0002-8334-0013","position":10,"is_corresponding":false},{"id":250787,"name":"Raymond K. Cross","orcid":"0000-0001-9766-5196","position":11,"is_corresponding":false},{"id":235302,"name":"Millie D. Long","orcid":"0000-0001-5983-2758","position":12,"is_corresponding":false},{"id":233525,"name":"Hans Herfarth","orcid":"0000-0003-4268-823X","position":13,"is_corresponding":false},{"id":280893,"name":"Edward L. Barnes","orcid":"0000-0001-9894-8796","position":0,"is_corresponding":true}],"reference_count":42,"raw_metadata":null,"created_at":"2026-07-19T00:26:29.321923Z","pmid":"36082341","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}