{"doi":"10.1093/clinchem/16.11.925","title":"Prediction of Haptoglobin and α2-Macroglobulin Concentrations from Electrophoretic Patterns of Serum α2-Globulin","abstract":"<jats:title>Abstract</jats:title>\n               <jats:p>Cellulose—acetate electrophoretic densitometry patterns for α2-globulin have been analyzed, with sera from 150 patients. The mobility of serum α2-macroglobulin exceeds that of haptoglobin to the extent that certain patterns correlate with abnormal concentrations of one or both of these proteins in serum. The most readily recognizable patterns occur when there is a major increase in one protein and the other remains normal. A very low value for one protein, particularly haptoglobin, can also be recognized. Concentration of these two proteins can be roughly predicted under definable circumstances.</jats:p>","journal":"Clinical Chemistry","year":1970,"id":649938,"datarank":0.29188652235829704,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.0,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1694543,"name":"Eleonore Elzer","orcid":null,"position":1,"is_corresponding":false},{"id":1694544,"name":"Alec Gabe","orcid":null,"position":2,"is_corresponding":false},{"id":1694542,"name":"M Henry Gault","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Prediction of Haptoglobin and α2-Macroglobulin Concentrations from Electrophoretic Patterns of Serum α2-Globulin","abstract":"<jats:title>Abstract</jats:title>\n               <jats:p>Cellulose—acetate electrophoretic densitometry patterns for α2-globulin have been analyzed, with sera from 150 patients. The mobility of serum α2-macroglobulin exceeds that of haptoglobin to the extent that certain patterns correlate with abnormal concentrations of one or both of these proteins in serum. The most readily recognizable patterns occur when there is a major increase in one protein and the other remains normal. A very low value for one protein, particularly haptoglobin, can also be recognized. Concentration of these two proteins can be roughly predicted under definable circumstances.</jats:p>","is_dataset_classified":null,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"4097405","pmcid":null,"openalex_id":"https://openalex.org/W1930396412","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.09976551,"influential_citations":0,"citation_trend":[{"year":2017,"count":2}],"oa_status":"closed","license":"https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model","oa_locations":[{"url":"http://academic.oup.com/clinchem/article-pdf/16/11/925/32821733/clinchem0925.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1093/clinchem/16.11.925","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/4097405","host_type":"repository"}],"fields_of_study":["Microfluidic and Capillary Electrophoresis Applications","Hemoglobin structure and function","Mass Spectrometry Techniques and Applications"],"mesh_terms":["Acetates","Adult","Alpha-Globulins","Anemia, Hemolytic","Blood Protein Electrophoresis","Cellulose","Densitometry","Female","Immunodiffusion","Haptoglobins","Humans","Immune Sera","Macroglobulins","Male","Methods"],"keywords":["Haptoglobin","Macroglobulin","Blood proteins","Cellulose acetate","Globulin","Electrophoresis","Densitometry","Beta globulins","alpha-2-Macroglobulin","Immunoelectrophoresis","Chemistry","Blood protein electrophoresis","Biochemistry","Biology","Gamma globulin","Immunology","Internal medicine","Medicine","Cellulose","Antibody"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-10T04:33:22.701726Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}