{"doi":"10.1093/bioinformatics/btx517","title":"MAPseq: highly efficient k-mer search with confidence estimates, for rRNA sequence analysis","abstract":"<h4>Motivation</h4>Ribosomal RNA profiling has become crucial to studying microbial communities, but meaningful taxonomic analysis and inter-comparison of such data are still hampered by technical limitations, between-study design variability and inconsistencies between taxonomies used.<h4>Results</h4>Here we present MAPseq, a framework for reference-based rRNA sequence analysis that is up to 30% more accurate (F½ score) and up to one hundred times faster than existing solutions, providing in a single run multiple taxonomy classifications and hierarchical operational taxonomic unit mappings, for rRNA sequences in both amplicon and shotgun sequencing strategies, and for datasets of virtually any size.<h4>Availability and implementation</h4>Source code and binaries are freely available at https://github.com/jfmrod/mapseq.<h4>Contact</h4>mering@imls.uzh.ch.<h4>Supplementary information</h4>Supplementary data are available at Bioinformatics online.","journal":"Bioinformatics","year":2017,"id":6389,"datarank":0.7525919755222388,"base_score":5.017279836814924,"endowment":5.017279836814924,"self_citation_contribution":0.7525919755222388,"citation_network_contribution":0.0,"self_endowment_contribution":0.7525919755222388,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":150,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.0455,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2017-08-14","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":59149,"name":"Thomas S B Schmidt","orcid":null,"position":1,"is_corresponding":false},{"id":59150,"name":"Janko Tackmann","orcid":"0000-0003-1467-2863","position":2,"is_corresponding":false},{"id":13184,"name":"Christian von Mering","orcid":"0000-0001-7734-9102","position":3,"is_corresponding":false},{"id":59151,"name":"Thomas Schmidt","orcid":"0000-0001-8587-4177","position":4,"is_corresponding":false},{"id":59148,"name":"João F. Matias Rodrigues","orcid":"0000-0001-8413-9920","position":0,"is_corresponding":true}],"reference_count":7,"raw_metadata":null,"created_at":"2026-03-01T18:20:47.508186Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}