{"doi":"10.1093/annonc/mdh263","title":"Chromosomal abnormalities of 200 Chinese patients with non-Hodgkin's lymphoma in Taiwan: with special reference to T-cell lymphoma","abstract":null,"journal":"Annals of Oncology","year":2004,"id":598511,"datarank":0.5495342469194471,"base_score":3.6635616461296463,"endowment":3.6635616461296463,"self_citation_contribution":0.5495342469194471,"citation_network_contribution":0.0,"self_endowment_contribution":0.5495342469194471,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":38,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":803957,"name":"M. Yao","orcid":"0009-0006-9572-6737","position":1,"is_corresponding":false},{"id":1533687,"name":"J.-L. Tang","orcid":null,"position":2,"is_corresponding":false},{"id":1533688,"name":"W. Tsay","orcid":null,"position":3,"is_corresponding":false},{"id":1533689,"name":"C.-C. Wang","orcid":null,"position":4,"is_corresponding":false},{"id":794602,"name":"W.-C. Chou","orcid":null,"position":5,"is_corresponding":false},{"id":1533690,"name":"I.-J. Su","orcid":null,"position":6,"is_corresponding":false},{"id":1533692,"name":"F.-Y. Lee","orcid":null,"position":7,"is_corresponding":false},{"id":1533693,"name":"M.-C. Liu","orcid":null,"position":8,"is_corresponding":false},{"id":1533694,"name":"H.-F. Tien","orcid":null,"position":9,"is_corresponding":false},{"id":149381,"name":"C.-Y. Chen","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Chromosomal abnormalities of 200 Chinese patients with non-Hodgkin's lymphoma in Taiwan: with special reference to T-cell lymphoma","abstract":"<h4>Background</h4>The distribution of the histopathological subtypes of non-Hodgkin's lymphoma (NHL) is different among various geographical areas. However, there are few reports concerning cytogenetic findings of NHL, especially T-cell lymphoma, in Asian people.<h4>Patients and methods</h4>We analyzed the chromosomal abnormalities of 200 adult patients with NHL in Taiwan and correlated the non-random aberrations with the histological subtypes.<h4>Results</h4>One hundred and thirty-eight patients (69%) had B-cell lymphoma. The incidence of the t(14;18) in total lymphoma was lower in Taiwan (12%) than in the West (20-30%), but its incidence in follicular lymphoma was comparable between the two areas (17 of 28 patients, 61% versus approximately 50-60%). Sixty-two patients (31%) had T-cell lymphoma, including 11 angiocentric T/natural killer (NK)-cell lymphoma and only two angioimmunoblastic T-cell lymphoma (AILD). The recurrent chromosomal abnormalities in T-cell lymphoma comprised 6q deletion (30%), 11q deletion (20%), 17p deletion (16%), -17 (16%), -Y (14%) and + 8 (11%). Angiocentric T/NK-cell lymphoma had a significantly higher frequency of 1q duplication (P=0.001), 6p duplication (P <0.001) and 11q deletion (P=0.011) than other T-cell lymphoma. The incidences of +3 and +5, two common abnormalities in AILD, were quite low in T-cell lymphoma in Taiwan (4% and 2%, respectively), compared with those in the West (16-32% and approximately 15%, respectively). The 11q deletion, not a common aberration in T-cell lymphoma in western countries, occurred quite frequently in Taiwan.<h4>Conclusions</h4>The chromosomal aberrations of NHL are quite different among various geographical areas, which may reflect the differences in the distribution of the histological subtypes of lymphoma among various areas.","is_dataset_classified":null,"base_score":3.6635616461296463,"endowment":3.6635616461296463,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"15205204","pmcid":null,"openalex_id":"https://openalex.org/W2135253367","authors":[],"funders":[],"total_grants":0,"fwci":1.4313,"citation_percentile":0.81165049,"influential_citations":0,"citation_trend":[{"year":2012,"count":4},{"year":2013,"count":3},{"year":2014,"count":3},{"year":2015,"count":2},{"year":2016,"count":2},{"year":2017,"count":2},{"year":2019,"count":1},{"year":2020,"count":1},{"year":2021,"count":3},{"year":2023,"count":1}],"oa_status":"closed","license":"http://www.elsevier.com/open-access/userlicense/1.0/","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0923753419480216?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0923753419480216?httpAccept=text/plain","host_type":"publisher"},{"url":"http://academic.oup.com/annonc/article-pdf/15/7/1091/676676/mdh263.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1093/annonc/mdh263","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/15205204","host_type":"repository"}],"fields_of_study":["Lymphoma Diagnosis and Treatment","CNS Lymphoma Diagnosis and Treatment","T-cell and Retrovirus Studies"],"mesh_terms":["Adult","Aged","Aged, 80 and over","Bone Marrow Cells","Chromosome Aberrations","Chromosome Deletion","Humans","Karyotyping","Lymph Nodes","Lymphoma, Non-Hodgkin","Middle Aged","Taiwan","Lymphoma, B-Cell","Lymphoma, T-Cell","Gene Duplication"],"keywords":["Lymphoma","T-cell lymphoma","Medicine","Follicular lymphoma","Incidence (geometry)","Pathology","Non-Hodgkin's lymphoma","Large cell","Internal medicine","Cancer","Adenocarcinoma"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Partnerships for the goals"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-28T15:50:18.735491Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}