{"doi":"10.1093/alcalc/agr106","title":"S16 * ALCOHOLIC LIVER DISEASE AND LIVER TRANSPLANTATION * S16.3 * RELAPSE OF HARMFUL DRINKING IN LIVER-TRANSPLANTED ALCOHOLICS: RISK STRATIFICATION AND CHALLENGE TO THE 6-MONTH RULE","abstract":null,"journal":"Alcohol and Alcoholism","year":2011,"id":684634,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1311490,"name":"C. Moreno","orcid":null,"position":1,"is_corresponding":false},{"id":1639626,"name":"M. Soyka","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"S16 * ALCOHOLIC LIVER DISEASE AND LIVER TRANSPLANTATION * S16.3 * RELAPSE OF HARMFUL DRINKING IN LIVER-TRANSPLANTED ALCOHOLICS: RISK STRATIFICATION AND CHALLENGE TO THE 6-MONTH RULE","abstract":"Alcoholic liver diesease (ALD) is still the most frequent and lethal complication in chronic alcoholism. Primary treatment modalities are abstinence, agents that suppress inflammation, anticytokine therapy and nutritional support, among others. For alcoholic liver cirrhosis, transplantation is an accepted option but requires careful consideration of alcohol history and future prognosis resp treatment options. Although there is a relationship between the lemgth of sobriety and future abstience, the present methods to predict future drinking are inexact. Approximately 20% of patients return to harmful drinking after transplantation (Lucey, 2011). Compared with other patient groups, relapse rates in patients with ALD are low. A number of other clinical variables apart from length of abstinence (Tandon et al., 2008) may predict outcome as alcohol research shows. This may include alcohol-associated symptoms, previous treatments and psychopathological symptoms including cogntion and history of suicide attempts. In general, DSM-IV-Tr alcoholism criteria appear to have greater utility for predicting survival differences beyond pathophysiologically defined alcoholic liver failure (Rowley et al., 2010). Implications for diagnosis and treatment are discussed. REFERENCES Lucey M (2011) Liver transplantaion in patients with alcoholic liver disease. Liver Transpl, doi. 10.1002/lt.22330. Rowley AA, Hong BA, Chapmna W et al. (2010) The psychiatric disgnosis of alcohol abuse and the medical diagnosis of alcoholic related liver disease: effect on liver transplant survival. J Clin Psychol Med Settings17:195–202. Tandon P, Goodman KJ, Ka MM et al. (2009) A shorter duration of pre-transplant abstinence predicts problem drinking after liver transplantation. Am J Gastroenterol104:1700–1706.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"26207759","pmcid":null,"openalex_id":"https://openalex.org/W2274444962","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":null,"oa_locations":[{"url":"http://academic.oup.com/alcalc/article-pdf/46/suppl_1/i14/424563/agr106.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1093/alcalc/agr106","host_type":"journal"}],"fields_of_study":["Alcohol Consumption and Health Effects"],"mesh_terms":[],"keywords":["Alcoholic liver disease","Abstinence","Liver transplantation","Medicine","Alcoholic hepatitis","Liver disease","Transplantation","Cirrhosis","Internal medicine","Sobriety","Gastroenterology","Psychiatry"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T14:37:31.717825Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}