{"doi":"10.1093/ajh/hpaf017","title":"The Diagnostic Accuracy of Using Borderline High Office Blood Pressure Thresholds to Diagnose Masked Hypertension According to the 2017 American College of Cardiology/American Heart Association Blood Pressure Guideline","abstract":"BACKGROUND: The 2017 American College of Cardiology (ACC)/American Heart Association (AHA) BP guideline recommends ambulatory BP monitoring (ABPM) for diagnosing masked hypertension among adults not taking antihypertensive medication with borderline office BP (i.e., office systolic BP [SBP] 120 to < 130 mm Hg or diastolic BP [DBP] 75 to < 80 mm Hg). METHODS: Using data from the Improving the Detection of Hypertension Study, sensitivity (SN), specificity (SP), positive predictive value (PPV), negative predictive value (NPV), and likelihood ratios for a positive and negative test of having borderline office BP (i.e., office SBP 120 to < 130 mm Hg or DBP 75 to < 80 mm Hg) for diagnosing masked hypertension (i.e., mean awake SBP ≥ 130 mm Hg or mean awake DBP ≥ 80 mm Hg) were determined among 263 participants who had a mean office SBP < 130 mm Hg and mean DBP < 80 mm Hg. Likelihood ratios for a positive test > 10, 5-10, and < 5 were considered strong, moderate, and weak, respectively. Likelihood ratios for a negative test < 0.1, 0.1-0.2, and > 0.2 were considered strong, moderate, and weak, respectively. RESULTS: Among the 263 participants, mean ± SD age was 39.2 ± 12.8 years, 62.4% were female, 38.4% had borderline office BP, and 26.2% had masked hypertension. SN, SP, PPV, and NPV were 0.754, 0.747, 0.515, and 0.895, respectively. The likelihood ratios for a positive and negative test were 2.984 (weak) and 0.330 (weak), respectively. CONCLUSIONS: The use of borderline office BP thresholds recommended in the 2017 ACC/AHA BP guideline did not sufficiently rule in or rule out masked hypertension.","journal":"American Journal of Hypertension","year":2025,"id":529923,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9658,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":413140,"name":"Eun Hee Choi","orcid":"0000-0002-3449-0672","position":1,"is_corresponding":false},{"id":1085434,"name":"Chloe Fang","orcid":null,"position":2,"is_corresponding":false},{"id":1409252,"name":"Keisuke Narita","orcid":"0000-0002-2020-898X","position":3,"is_corresponding":false},{"id":1004256,"name":"Maria Cepeda","orcid":"0009-0006-3332-1953","position":4,"is_corresponding":false},{"id":339180,"name":"Brulinda Frangaj","orcid":"0000-0002-1206-3872","position":5,"is_corresponding":false},{"id":1409706,"name":"Sofia Kim","orcid":null,"position":6,"is_corresponding":false},{"id":1409707,"name":"Yaniris Mercado","orcid":null,"position":7,"is_corresponding":false},{"id":442590,"name":"Riley Nesheim-Case","orcid":null,"position":8,"is_corresponding":false},{"id":1409708,"name":"Uriel Alvira Ramirez","orcid":null,"position":9,"is_corresponding":false},{"id":1338829,"name":"Matthew Barrett","orcid":"0000-0002-5025-0732","position":10,"is_corresponding":false},{"id":106993,"name":"Joseph E. Schwartz","orcid":"0000-0002-8944-3566","position":11,"is_corresponding":false},{"id":281843,"name":"Daichi Shimbo","orcid":"0000-0001-6302-8834","position":12,"is_corresponding":false},{"id":1409705,"name":"Sophie Walsh","orcid":null,"position":0,"is_corresponding":true}],"reference_count":28,"raw_metadata":null,"created_at":"2026-07-19T02:51:01.235017Z","pmid":"39893503","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}