{"doi":"10.1093/aje/kwae066","title":"Current use of estrogen-containing oral contraceptives or hormone therapy and risk of COVID-19 infection and hospitalization: a population-based cohort study","abstract":"The association between current use of oral contraceptives (OCs) among women younger than 50 years (n = 306 541), and hormone therapy (HT) among women aged 50 years or older (n = 323 203), and coronavirus 2019 (COVID-19) infection and hospitalization was evaluated in this population-based cohort. Current OC/HT use was recorded monthly using prescription dispensing data. COVID-19 infections were identified from March 2020 through February 2021. COVID-19 infections and hospitalizations were identified through diagnosis codes and laboratory tests. We used weighted generalized estimating equations models to estimate multivariable adjusted odds ratios (aORs) for COVID-19 infection associated with time-varying OC/HT use. Among women with COVID-19, logistic regression models were used to evaluate OC/HT use and COVID-19 hospitalization. Over 12 months, 11 727 (3.8%) women younger than 50 years and 8661 (2.7%) women aged 50 years or older experienced COVID-19 infections. There was no evidence of an association between OC use and infection (aOR = 1.05; 95% CI, 0.97-1.12). There was a modest association between HT use and infection (aOR = 1.19; 95% CI, 1.03-1.38). Women using OCs had a 39% lower risk of hospitalization (aOR = 0.61; 95% CI, 0.38-1.00), but there was no association of HT use with hospitalization (aOR = 0.89; 95% CI, 0.51-1.53). These findings do not suggest a meaningfully greater risk of COVID-19 infection associated with OC or HT use. OC use may be associated with lower COVID-19 hospitalization risk.","journal":"American Journal of Epidemiology","year":2024,"id":480145,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9124,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":450749,"name":"J. David Powers","orcid":"0000-0003-2779-3402","position":1,"is_corresponding":false},{"id":251910,"name":"Elizabeth A. Bayliss","orcid":"0000-0002-5264-0670","position":2,"is_corresponding":false},{"id":361487,"name":"Stephen P. Fortmann","orcid":"0000-0002-1327-9341","position":3,"is_corresponding":false},{"id":422126,"name":"Susan M. Shortreed","orcid":"0000-0001-7918-601X","position":4,"is_corresponding":false},{"id":302264,"name":"Rod Walker","orcid":"0000-0002-8464-9805","position":5,"is_corresponding":false},{"id":51218,"name":"James S. Floyd","orcid":"0000-0002-0365-9041","position":6,"is_corresponding":false},{"id":525074,"name":"Jennifer L. Kuntz","orcid":"0000-0002-0017-6853","position":7,"is_corresponding":false},{"id":894155,"name":"Sharon Fuller","orcid":"0009-0001-1198-1225","position":8,"is_corresponding":false},{"id":1319784,"name":"Ladia Alberston-Junkans","orcid":null,"position":9,"is_corresponding":false},{"id":1319446,"name":"Mi H. Lee","orcid":"0009-0002-1983-7305","position":10,"is_corresponding":false},{"id":1319785,"name":"Lisa A. Temposky","orcid":null,"position":11,"is_corresponding":false},{"id":494403,"name":"Sascha Dublin","orcid":"0000-0002-6649-3659","position":12,"is_corresponding":false},{"id":1248081,"name":"Laura B. Harrington","orcid":"0000-0001-5951-8291","position":0,"is_corresponding":true}],"reference_count":33,"raw_metadata":null,"created_at":"2026-07-19T02:06:58.305365Z","pmid":"38751326","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}