{"doi":"10.1093/abm/kaaa056","title":"Evaluation of a Text Messaging-Based Human Papillomavirus Vaccination Intervention for Young Sexual Minority Men: Results from a Pilot Randomized Controlled Trial","abstract":"BACKGROUND: Men who have sex with men (MSM) are at high risk for human papillomavirus (HPV) infection and HPV-related anal cancer. Although a safe and effective vaccine is available to prevent HPV infection, HPV vaccine uptake among young MSM remains low. PURPOSE: This pilot randomized controlled trial tested the acceptability, feasibility, and preliminary efficacy of a text messaging-based HPV vaccination intervention for young sexual minority men. METHODS: In 2018, unvaccinated sexual minority men aged 18-25 years were recruited from Chicago to participate in a 9 month sexual health program called txt2protect. Participants (N = 150) were randomized to the intervention or control condition. Intervention condition messages focused primarily on HPV vaccination, with only a brief mention of other sexual health practices (e.g., condom use and HIV testing), while control condition messages focused on a variety of sexual health practices with only a brief mention of HPV vaccination. Participants received daily text messages for the first 3 weeks and monthly text messages for the remaining ~8 months of the trial. Participants completed surveys at baseline and 3 week and 9 month follow-ups. RESULTS: Participants reported high satisfaction with the intervention. Although trial retention was high (with over 88% completing the 9 month survey), the study fell short of meeting its recruitment goal. HPV vaccine series initiation was significantly higher among intervention participants (19.4%) compared to control participants (6.6%), odds ratio = 3.43, 95% confidence interval: 1.17, 10.08. CONCLUSIONS: Findings suggest that txt2protect is an acceptable and potentially promising intervention for increasing HPV vaccine initiation among young sexual minority men. CLINICAL TRIAL REGISTRATION: NCT02994108.","journal":"Annals of Behavioral Medicine","year":2020,"id":64267,"datarank":1.3012349939372672,"base_score":3.6109179126442243,"endowment":3.6109179126442243,"self_citation_contribution":0.5416376868966337,"citation_network_contribution":0.7595973070406336,"self_endowment_contribution":0.5416376868966337,"citer_contribution":0.7595973070406336,"corpus_percentile":null,"corpus_rank":null,"citation_count":36,"citer_count":34,"citers_with_citation_signal":21,"citers_with_endowment":21,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9566,"is_data_producer":true,"deposit_databanks":{"ClinicalTrials.gov":["NCT02994108"]},"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":339823,"name":"Krystal Madkins","orcid":"0000-0002-3574-8006","position":1,"is_corresponding":false},{"id":340928,"name":"Shariell Crosby","orcid":null,"position":2,"is_corresponding":false},{"id":340929,"name":"Aaron K. Korpak","orcid":null,"position":3,"is_corresponding":false},{"id":339824,"name":"Gregory Phillips","orcid":"0000-0001-8396-1170","position":4,"is_corresponding":false},{"id":339825,"name":"Michael Bass","orcid":"0000-0002-7732-6557","position":5,"is_corresponding":false},{"id":340930,"name":"Magda Houlberg","orcid":null,"position":6,"is_corresponding":false},{"id":339826,"name":"Brian Mustanski","orcid":"0000-0001-9222-5116","position":7,"is_corresponding":false},{"id":339822,"name":"Mary A. Gerend","orcid":"0000-0001-5413-1426","position":0,"is_corresponding":true}],"reference_count":52,"raw_metadata":null,"created_at":"2026-07-18T21:12:32.635050Z","pmid":"32914838","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}