{"doi":"10.1089/g4h.2022.0118","title":"Usage of RePlay as a Take-Home System to Support High-Repetition Motor Rehabilitation After Neurological Injury","abstract":"Stroke is a leading cause of chronic motor disability. While physical rehabilitation can promote functional recovery, several barriers prevent patients from receiving optimal rehabilitative care. Easy access to at-home rehabilitative tools could increase patients' ability to participate in rehabilitative exercises, which may lead to improved outcomes. Toward achieving this goal, we developed RePlay: a novel system that facilitates unsupervised rehabilitative exercises at home. RePlay leverages available consumer technology to provide a simple tool that allows users to perform common rehabilitative exercises in a gameplay environment. RePlay collects quantitative time series force and movement data from handheld devices, which provide therapists the ability to quantify gains and individualize rehabilitative regimens. RePlay was developed in C# using Visual Studio. In this feasibility study, we assessed whether participants with neurological injury are capable of using the RePlay system in both a supervised in-office setting and an unsupervised at-home setting, and we assessed their adherence to the unsupervised at-home rehabilitation assignment. All participants were assigned a set of 18 games and exercises to play each day. Participants produced on average 698 ± 36 discrete movements during the initial 1 hour in-office visit. A subset of participants who used the system at home produced 1593 ± 197 discrete movements per day. Participants demonstrated a high degree of engagement while using the system at home, typically completing nearly double the number of assigned exercises per day. These findings indicate that the open-source RePlay system may be a feasible tool to facilitate access to rehabilitative exercises and potentially improve overall patient outcomes.","journal":"Games for Health Journal","year":2022,"id":277169,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.958,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":948743,"name":"Y.-Nhy Duong-Nguyen","orcid":null,"position":1,"is_corresponding":false},{"id":948205,"name":"Eric Meyers","orcid":"0000-0002-2013-5450","position":2,"is_corresponding":false},{"id":725734,"name":"Joseph Epperson","orcid":"0000-0002-6430-8472","position":3,"is_corresponding":false},{"id":948744,"name":"Joel M. Wright","orcid":null,"position":4,"is_corresponding":false},{"id":948745,"name":"Rachael A. Hudson","orcid":null,"position":5,"is_corresponding":false},{"id":655529,"name":"Jane G. Wigginton","orcid":"0000-0002-8561-3492","position":6,"is_corresponding":false},{"id":308779,"name":"Robert L. Rennaker","orcid":"0000-0003-1260-1973","position":7,"is_corresponding":false},{"id":308781,"name":"Seth A. Hays","orcid":"0000-0003-4225-241X","position":8,"is_corresponding":false},{"id":308780,"name":"Michael P. Kilgard","orcid":"0000-0002-6699-1818","position":9,"is_corresponding":false},{"id":310044,"name":"David Pruitt","orcid":null,"position":0,"is_corresponding":true}],"reference_count":57,"raw_metadata":null,"created_at":"2026-07-19T00:28:34.768552Z","pmid":"36318505","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}