{"doi":"10.1089/aid.2020.0046","title":"Comparison of HIV Incidence in the Zimbabwe Population-Based HIV Impact Assessment Survey (2015–2016) with Modeled Estimates: Progress Toward Epidemic Control","abstract":"Between October 2015 and August 2016, Zimbabwe conducted the Zimbabwe Population-Based HIV Impact Assessment (ZIMPHIA) cross-sectional survey to determine progress toward epidemic control. Of 25,131 eligible adults aged 15-64 years, 20,577 (81.8%) consented to face-to-face questionnaire and biomarker testing in this nationally representative household survey. Home-based rapid HIV testing was performed using Determine, First Response, and STAT-PAK as the tiebreaker. HIV-positive tests were confirmed in a laboratory using Geenius HIV-1/2; viral load (VL) was measured using Roche TaqMan and BioMerieux NucliSENS. Recency of infection was tested using Sedia HIV-1 Limiting Antigen (LAg)-Avidity. Presence of antiretroviral (ARV) drugs was detected using high performance liquid chromatography/mass spectrometry (HPLC/MS). The recent infection testing algorithm included LAg-avidity enzyme immunoassay [normalized optical density (ODn ≤1.5), VL ≥1,000 copies/mL, and absence of ARV drugs]. Weighted annual HIV incidence was compared with United Nations Joint Programme on HIV/AIDS (UNAIDS) Spectrum models estimates. Overall, 26 of 2,901 HIV-seropositive individuals had a recent infection (men, 8; women, 18). Overall weighted annual incidence among persons aged 15-64 years was 0.42% [95% confidence interval (CI): 0.25-0.59] and was 0.44% (95% CI: 0.25-0.62) for those aged 15-49 years, similar to 2016 Spectrum model estimate (0.54%, 95% CI: 0.49-0.66) for this age group. Among persons aged 15-49 years, HIV prevalence was 13.35% (95% CI: 12.71-14.02), estimated HIV-positive individuals were 968,951 (95% CI: 911,473-1,026,430), of these, 41,911 (95% CI: 37,412-44,787) were annual-new infections, and this was similar to 2016 Spectrum estimates. The observed HIV incidence in ZIMPHIA 2015-2016 validated the 2016 Spectrum estimates and Zimbabwe's progress toward epidemic control.","journal":"AIDS Research and Human Retroviruses","year":2020,"id":70454,"datarank":0.7865626848237535,"base_score":2.995732273553991,"endowment":2.995732273553991,"self_citation_contribution":0.4493598410330987,"citation_network_contribution":0.33720284379065474,"self_endowment_contribution":0.4493598410330987,"citer_contribution":0.33720284379065474,"corpus_percentile":74.4101492999149,"corpus_rank":3309,"citation_count":19,"citer_count":11,"citers_with_citation_signal":9,"citers_with_endowment":9,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.5635,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":372465,"name":"Godfrey Musuka","orcid":"0000-0001-9077-4429","position":1,"is_corresponding":false},{"id":373189,"name":"Leala Ruangtragool","orcid":null,"position":2,"is_corresponding":false},{"id":372466,"name":"Avi J. Hakim","orcid":"0000-0001-6754-6241","position":3,"is_corresponding":false},{"id":372467,"name":"Bharat Parekh","orcid":"0000-0002-1088-4263","position":4,"is_corresponding":false},{"id":372468,"name":"Trudy Dobbs","orcid":"0000-0002-3289-6011","position":5,"is_corresponding":false},{"id":373190,"name":"Yen T. Duong","orcid":null,"position":6,"is_corresponding":false},{"id":372469,"name":"Hetal Patel","orcid":"0000-0002-5468-2591","position":7,"is_corresponding":false},{"id":373191,"name":"Mutsa Mhangara","orcid":null,"position":8,"is_corresponding":false},{"id":372470,"name":"Owen Mugurungi","orcid":"0000-0001-7779-5583","position":9,"is_corresponding":false},{"id":372471,"name":"Munyaradzi Mapingure","orcid":"0000-0002-7777-9492","position":10,"is_corresponding":false},{"id":372472,"name":"Suzue Saito","orcid":"0000-0001-9725-5736","position":11,"is_corresponding":false},{"id":372473,"name":"Amy Herman-Roloff","orcid":"0000-0002-3027-5940","position":12,"is_corresponding":false},{"id":373192,"name":"Lovemore Gwanzura","orcid":null,"position":13,"is_corresponding":false},{"id":372474,"name":"Beth A. Tippett Barr","orcid":"0000-0001-5877-2968","position":14,"is_corresponding":false},{"id":372475,"name":"Peter H. Kilmarx","orcid":"0000-0001-6464-3345","position":15,"is_corresponding":false},{"id":372476,"name":"Jessica Justman","orcid":"0000-0003-4704-3115","position":16,"is_corresponding":false},{"id":372464,"name":"Elizabeth Gonese","orcid":"0000-0003-1045-4930","position":0,"is_corresponding":true}],"reference_count":14,"raw_metadata":null,"created_at":"2026-07-18T21:43:11.119231Z","pmid":"32498542","pmcid":"PMC7986968","fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}