{"doi":"10.1086/342953","title":"Polygenic Control of Human T Lymphotropic Virus Type I (HTLV‐I) Provirus Load and the Risk of HTLV‐I–Associated Myelopathy/Tropical Spastic Paraparesis","abstract":null,"journal":"The Journal of Infectious Diseases","year":2002,"id":588858,"datarank":3.0991874526597667,"base_score":4.543294782270004,"endowment":4.543294782270004,"self_citation_contribution":0.6814942173405006,"citation_network_contribution":2.417693235319266,"self_endowment_contribution":0.6814942173405006,"citer_contribution":2.417693235319266,"corpus_percentile":null,"corpus_rank":null,"citation_count":93,"citer_count":63,"citers_with_citation_signal":53,"citers_with_endowment":53,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1506611,"name":"Aviva D. 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The promoter TNF -863A allele predisposed to HAM/TSP, whereas SDF-1 +801A 3'UTR, and IL-15 191C alleles conferred protection. Knowledge of HTLV-I-infected individuals' ages, sex, provirus load, HTLV-I subgroup, and genotypes at the loci HLA-A, HLA-C, SDF-1, and TNF-alpha allowed for the correct identification of 88% of cases of HAM/TSP in this Japanese cohort.","is_dataset_classified":null,"base_score":4.543294782270004,"endowment":4.543294782270004,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"12232833","pmcid":null,"openalex_id":"https://openalex.org/W2123272094","authors":[],"funders":[],"total_grants":0,"fwci":1.7136,"citation_percentile":0.84320805,"influential_citations":0,"citation_trend":[{"year":2012,"count":4},{"year":2013,"count":5},{"year":2014,"count":3},{"year":2015,"count":3},{"year":2016,"count":4},{"year":2017,"count":1},{"year":2019,"count":3},{"year":2020,"count":1},{"year":2021,"count":1},{"year":2022,"count":1},{"year":2023,"count":1},{"year":2024,"count":3},{"year":2025,"count":2}],"oa_status":"closed","license":null,"oa_locations":[{"url":"http://academic.oup.com/jid/article-pdf/186/7/932/18008225/186-7-932.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1086/342953","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/12232833","host_type":"repository"},{"url":"http://www.lib.ncsu.edu/resolver/1840.2/157","host_type":"repository"},{"url":"http://researchrepository.murdoch.edu.au/id/eprint/5172/","host_type":"repository"},{"url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.567.6496","host_type":""},{"url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.948.5205","host_type":""}],"fields_of_study":["T-cell and Retrovirus Studies","Animal Disease Management and Epidemiology","Vector-Borne Animal Diseases","Alleles","Carrier State","Chemokine CXCL12","Chemokines, CXC","Cohort Studies","Genetic Predisposition to Disease","HLA-A Antigens","HLA-C Antigens","Human T-lymphotropic virus 1","Humans","Interleukin-15","Japan","Multifactorial Inheritance","Paraparesis, Tropical Spastic","Promoter Regions, Genetic","Proviruses","Tumor Necrosis Factor-alpha","Viral Load"],"mesh_terms":["Alleles","Carrier State","Humans","Japan","Promoter Regions, Genetic","Proviruses","Tumor Necrosis Factor-alpha","HLA-A Antigens","HLA-C Antigens","Cohort Studies","Human T-lymphotropic virus 1","Paraparesis, Tropical Spastic","Interleukin-15","Viral Load","Chemokines, CXC","Genetic Predisposition to Disease","Multifactorial Inheritance","Chemokine CXCL12"],"keywords":["Tropical spastic paraparesis","Provirus","Human T-lymphotropic virus","Virology","Allele","Biology","Genotype","Virus","Myelopathy","Immunology","Population","Medicine","Genetics","Gene","Spinal cord"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-22T23:13:27.033059Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}