{"doi":"10.1080/09540100903452122","title":"Reduced antigenicity of<i>β</i>-lactoglobulin by conjugation with glucose through controlled Maillard reaction conditions","abstract":null,"journal":"Food and Agricultural Immunology","year":2010,"id":594847,"datarank":0.5101796072493234,"base_score":3.4011973816621555,"endowment":3.4011973816621555,"self_citation_contribution":0.5101796072493234,"citation_network_contribution":0.0,"self_endowment_contribution":0.5101796072493234,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":29,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1522961,"name":"Yongkang Luo","orcid":null,"position":1,"is_corresponding":false},{"id":531465,"name":"Jing Lu","orcid":"0009-0003-2163-5427","position":2,"is_corresponding":false},{"id":832049,"name":"Ying Zhang","orcid":"0000-0003-2194-7116","position":3,"is_corresponding":false},{"id":1522960,"name":"Guanhao Bu","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Reduced antigenicity of<i>β</i>-lactoglobulin by conjugation with glucose through controlled Maillard reaction conditions","abstract":"Abstract The effect of weight ratio of protein to sugar (0.17–7.83), temperature (40–60°C) and time (24–120 h) on the antigenicity of β-lactoglobulin (β-LG) in conjugates of whey protein isolate (WPI) with glucose was investigated. Response surface methodology was used to carry out an optimisation of the reaction conditions leading to the minimum antigenicity of β-LG. Conjugation of WPI with glucose could reduce effectively the antigenicity of β-LG. This reduction of antigenicity could be controlled by regulating three independent variables (weight ratio of WPI to glucose, temperature and time). The model for optimal reaction conditions of a lower antigenicity of β-LG was established. Weight ratio of WPI to glucose had the greatest effect on the antigenicity of β-LG. Reaction time influenced the antigenicity of β-LG to a lesser extent.","is_dataset_classified":null,"base_score":3.4011973816621555,"endowment":3.4011973816621555,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"23304386","pmcid":null,"openalex_id":"https://openalex.org/W2008472229","authors":[],"funders":[],"total_grants":0,"fwci":4.4512,"citation_percentile":0.93025809,"influential_citations":0,"citation_trend":[{"year":2012,"count":3},{"year":2013,"count":3},{"year":2014,"count":2},{"year":2015,"count":2},{"year":2016,"count":1},{"year":2017,"count":3},{"year":2018,"count":5},{"year":2020,"count":1},{"year":2022,"count":1},{"year":2023,"count":1},{"year":2024,"count":1},{"year":2025,"count":1},{"year":2026,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"http://www.tandfonline.com/doi/pdf/10.1080/09540100903452122","host_type":"publisher"},{"url":"https://doi.org/10.1080/09540100903452122","host_type":"journal"}],"fields_of_study":["Proteins in Food Systems","Infant Nutrition and Health","Protein Hydrolysis and Bioactive Peptides"],"mesh_terms":[],"keywords":["Antigenicity","Chemistry","Maillard reaction","Whey protein isolate","Biochemistry","Whey protein","Antigen","Biology","Immunology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Clean water and sanitation"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-27T15:43:11.731778Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}