{"doi":"10.1074/jbc.270.34.20084","title":"Yeast Viral 20 S RNA Is Associated with Its Cognate RNA-dependent RNA Polymerase","abstract":null,"journal":"Journal of Biological Chemistry","year":1995,"id":604483,"datarank":0.975645326853841,"base_score":3.295836866004329,"endowment":3.295836866004329,"self_citation_contribution":0.4943755299006494,"citation_network_contribution":0.4812697969531916,"self_endowment_contribution":0.4943755299006494,"citer_contribution":0.4812697969531916,"corpus_percentile":null,"corpus_rank":null,"citation_count":26,"citer_count":16,"citers_with_citation_signal":10,"citers_with_endowment":10,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1550967,"name":"Luis M. Esteban","orcid":null,"position":1,"is_corresponding":false},{"id":1189120,"name":"Tsutomu Fujimura","orcid":"0000-0002-9457-6769","position":2,"is_corresponding":false},{"id":1550968,"name":"Nieves Rodríguez-Cousiño","orcid":null,"position":3,"is_corresponding":false},{"id":1189121,"name":"Rosa Esteban","orcid":"0000-0001-6804-7209","position":4,"is_corresponding":false},{"id":1550966,"name":"María P. García-Cuéllar","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Yeast Viral 20 S RNA Is Associated with Its Cognate RNA-dependent RNA Polymerase","abstract":"Most Saccharomyces cerevisiae strains carry in their cytoplasm 20 S RNA, a linear single-stranded RNA molecule of 2.5 kilobases in size. 20 S RNA copy number is greatly induced in stress conditions such as starvation, with up to 100,000 copies per cell. 20 S RNA has coding capacity for a protein of 91 kDa (p91) with sequences diagnostic of RNA-dependent RNA polymerases of (+) strand and double-stranded RNA viruses. We detected p91 in 20 S RNA-carrying strains with specific antisera. The amount of p91 in growing cells is higher than that of stationary cells and similar to the one in 20 S RNA-induced cells. Although 20 S RNA is not encapsidated into viral particles, p91 non-covalently forms a ribonucleoprotein complex with 20 S RNA. This suggests a role of p91 in the RNA to RNA synthesis processes required for 20 S RNA replication. Although the strain analyzed also harbors 23 S RNA, a closely related single-stranded RNA, 23 S RNA is not associated with p91 but with its putative RNA polymerase, p104. Similarly, 20 S RNA is not associated with p104 but with p91. These results suggest that 20 S RNA and 23 S RNA replicate independently using their respective cognate RNA polymerases.","is_dataset_classified":null,"base_score":3.295836866004329,"endowment":3.295836866004329,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"7650026","pmcid":null,"openalex_id":"https://openalex.org/W2038243974","authors":[],"funders":[],"total_grants":0,"fwci":0.7526,"citation_percentile":0.70265638,"influential_citations":0,"citation_trend":[{"year":2013,"count":1},{"year":2014,"count":2},{"year":2015,"count":3},{"year":2020,"count":1},{"year":2021,"count":1},{"year":2023,"count":1}],"oa_status":"hybrid","license":"cc-by","oa_locations":[{"url":"http://www.jbc.org/article/S002192581894593X/pdf","host_type":"journal"},{"url":"http://www.jbc.org/article/S002192581894593X/pdf","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S002192581894593X?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S002192581894593X?httpAccept=text/plain","host_type":"publisher"},{"url":"https://syndication.highwire.org/content/doi/10.1074/jbc.270.34.20084","host_type":"publisher"},{"url":"https://doi.org/10.1074/jbc.270.34.20084","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/7650026","host_type":"repository"},{"url":"http://www.jbc.org/content/270/34/20084.full.pdf","host_type":"Unpaywall"}],"fields_of_study":["Plant and Fungal Interactions Research","Plant Virus Research Studies","RNA and protein synthesis mechanisms","Fungal Proteins","Gene Expression","RNA Viruses","RNA, Fungal","RNA, Viral","RNA-Dependent RNA Polymerase","Ribonucleoproteins","Saccharomyces cerevisiae","Viral Proteins"],"mesh_terms":["Fungal Proteins","Ribonucleoproteins","RNA-Dependent RNA Polymerase","RNA Viruses","RNA, Fungal","RNA, Viral","Saccharomyces cerevisiae","Viral Proteins","Gene Expression"],"keywords":["RNA","Small nuclear RNA","RNA-dependent RNA polymerase","RNA polymerase I","Non-coding RNA","RNA editing","Biology","Intron","RNA silencing","Molecular biology","Signal recognition particle RNA","Post-transcriptional modification","RNA polymerase","Nuclease protection assay","Genetics","Gene","RNA interference"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-30T00:14:46.139515Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}