{"doi":"10.1073/pnas.1706694115","title":"Chronic sleep curtailment, even without extended (&gt;16-h) wakefulness, degrades human vigilance performance","abstract":"<jats:title>Significance</jats:title>\n                  <jats:p>Millions of individuals obtain insufficient sleep on a daily basis, which leads to impaired performance. Whether these decrements are caused by short sleep duration or extended wakefulness is unknown. In this study, healthy volunteers were randomized into either a chronically sleep-restricted or control protocol while living on a 20-h “day,” thus enabling short sleep without extended wakefulness. We demonstrate that chronic insufficient sleep, even without extended wakefulness, leads to neurobehavioral performance decrements at all times of the day, even when the circadian system is promoting arousal. These findings have implications for the understanding of basic physiology, the substantial population who chronically obtains insufficient sleep, and all of us who depend on sleep-restricted individuals working in safety-sensitive occupations.</jats:p>","journal":"Proceedings of the National Academy of Sciences","year":2018,"id":41241,"datarank":2.0590713587824414,"base_score":4.356708826689592,"endowment":4.356708826689592,"self_citation_contribution":0.6535063240034389,"citation_network_contribution":1.4055650347790025,"self_endowment_contribution":0.6535063240034389,"citer_contribution":1.4055650347790025,"corpus_percentile":null,"corpus_rank":null,"citation_count":77,"citer_count":54,"citers_with_citation_signal":42,"citers_with_endowment":42,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":198943,"name":"Joseph T. Hull","orcid":null,"position":1,"is_corresponding":false},{"id":7625,"name":"Wei Wang","orcid":"0000-0002-9861-5577","position":2,"is_corresponding":false},{"id":197642,"name":"Charles A. Czeisler","orcid":null,"position":3,"is_corresponding":false},{"id":198944,"name":"Elizabeth B. Klerman","orcid":"0000-0002-7402-3171","position":4,"is_corresponding":false},{"id":198942,"name":"Andrew W. McHill","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":4.356708826689592,"endowment":4.356708826689592,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"29784810","pmcid":"PMC6003377","openalex_id":"https://openalex.org/W2803731958","authors":[],"funders":[{"funder_name":"HHS | NIH | National Center for Advancing Translational Sciences","grant_id":"KL2TR002370","title":null},{"funder_name":"HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases","grant_id":"F32DK107146","title":null},{"funder_name":"HHS | NIH | National Heart, Lung, and Blood Institute","grant_id":"T32HL007901","title":null},{"funder_name":"HHS | NIH | National Heart, Lung, and Blood Institute","grant_id":"K24HL105664","title":null},{"funder_name":"HHS | NIH | National Heart, Lung, and Blood Institute","grant_id":"R01HL114088","title":null},{"funder_name":"HHS | NIH | National Heart, Lung, and Blood Institute","grant_id":"R01HL128538","title":null},{"funder_name":"HHS | NIH | National Institute of General Medical Sciences","grant_id":"R01GM105018","title":null},{"funder_name":"HHS | NIH | National Institute on Aging","grant_id":"P01AG009975","title":null},{"funder_name":"HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development","grant_id":"R21HD086392","title":null},{"funder_name":"National Space Biomedical Research Institute","grant_id":"HFP02802","title":null},{"funder_name":"National Space Biomedical Research Institute","grant_id":"HFP04201","title":null},{"funder_name":"National Space Biomedical Research Institute","grant_id":"HDP0006","title":null},{"funder_name":"NCRR NIH HHS","grant_id":"M01 RR002635","title":null},{"funder_name":"NCRR NIH HHS","grant_id":"UL1 RR025758","title":null},{"funder_name":"NCATS NIH HHS","grant_id":"UL1 TR001102","title":null}],"total_grants":15,"fwci":7.8827,"citation_percentile":0.97609883,"influential_citations":0,"citation_trend":[{"year":2018,"count":6},{"year":2019,"count":12},{"year":2020,"count":8},{"year":2021,"count":10},{"year":2022,"count":12},{"year":2023,"count":12},{"year":2024,"count":6},{"year":2025,"count":7},{"year":2026,"count":4}],"oa_status":"bronze","license":"http://www.pnas.org/site/aboutpnas/licenses.xhtml","oa_locations":[{"url":"https://www.pnas.org/content/pnas/115/23/6070.full.pdf","host_type":"journal"},{"url":"https://www.pnas.org/content/pnas/115/23/6070.full.pdf","host_type":"BRONZE"},{"url":"https://www.pnas.org/content/pnas/115/23/6070.full.pdf","host_type":"publisher"},{"url":"http://www.pnas.org/syndication/doi/10.1073/pnas.1706694115","host_type":"publisher"},{"url":"https://pnas.org/doi/pdf/10.1073/pnas.1706694115","host_type":"publisher"},{"url":"https://doi.org/10.1073/pnas.1706694115","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/29784810","host_type":"repository"},{"url":"http://europepmc.org/pmc/articles/PMC6003377","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6003377","host_type":"repository"}],"fields_of_study":["Sleep and Work-Related Fatigue","Sleep and related disorders","Ergonomics and Musculoskeletal Disorders","Medicine","Adult","Arousal","Attention","Circadian Rhythm","Cognition","Female","Healthy Volunteers","Humans","Male","Polysomnography","Psychomotor Performance","Reaction Time","Self Report","Sleep","Sleep Deprivation","Sleep Wake Disorders","Time Factors","Wakefulness"],"mesh_terms":["Adult","Arousal","Attention","Circadian Rhythm","Cognition","Female","Humans","Male","Psychomotor Performance","Reaction Time","Sleep","Sleep Deprivation","Sleep Wake Disorders","Time Factors","Wakefulness","Polysomnography","Self Report","Healthy Volunteers"],"keywords":["Wakefulness","Arousal","Vigilance (psychology)","Sleep (system call)","Circadian rhythm","Sleep deprivation","Psychology","Population","Audiology","Medicine","Neuroscience","Electroencephalography","Computer science","Alertness","Sleepiness","Circadian","Forced Desynchrony","Insufficient Sleep"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"nct"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-12T22:36:24.665550Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}