{"doi":"10.1073/pnas.1402028111","title":"Ammonia-oxidizing archaea use the most energy-efficient aerobic pathway for CO\n            <sub>2</sub>\n            fixation","abstract":"<jats:title>Significance</jats:title>\n          <jats:p>\n            CO\n            <jats:sub>2</jats:sub>\n            fixation is the most important biosynthesis process on Earth, enabling autotrophic organisms to synthesize their entire biomass from inorganic carbon at the expense of energy generated by photo- or chemotrophic processes. In the present study we demonstrate an autotrophy pathway that represents the most energy-efficient mechanism for fixing inorganic carbon in the presence of oxygen. This novel variant of the hydroxypropionate/hydroxybutyrate cycle appears to be common in a ubiquitous and abundant group of microorganisms that can thrive in nutrient-limited environments. This discovery offers a biochemical explanation for the remarkable ecological success of the ammonia-oxidizing archaea in extremely nutrient-limited environments typical of most of the open ocean.\n          </jats:p>","journal":"Proceedings of the National Academy of Sciences","year":2014,"id":19747,"datarank":9.29761602816989,"base_score":6.230481447578482,"endowment":6.230481447578482,"self_citation_contribution":0.9345722171367724,"citation_network_contribution":8.363043811033117,"self_endowment_contribution":0.9345722171367724,"citer_contribution":8.363043811033117,"corpus_percentile":null,"corpus_rank":null,"citation_count":507,"citer_count":200,"citers_with_citation_signal":200,"citers_with_endowment":200,"datacite_reuse_total":25,"is_dataset":false,"is_dataset_confidence":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":132798,"name":"Daniel M. 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Berg","orcid":null,"position":9,"is_corresponding":false},{"id":132797,"name":"Martin Könneke","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":6.230481447578482,"endowment":6.230481447578482,"datacite_reuse_total":25,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"24843170","pmcid":"PMC4050595","openalex_id":"https://openalex.org/W2054287183","authors":[],"funders":[{"funder_name":"Swiss National Science Foundation","grant_id":"136828","title":"Reductive Carboxylases in Natural and Synthetic Microbial Pathways"}],"total_grants":1,"fwci":28.8135,"citation_percentile":0.99831953,"influential_citations":20,"citation_trend":[{"year":2014,"count":9},{"year":2015,"count":19},{"year":2016,"count":35},{"year":2017,"count":30},{"year":2018,"count":36},{"year":2019,"count":41},{"year":2020,"count":45},{"year":2021,"count":76},{"year":2022,"count":44},{"year":2023,"count":51},{"year":2024,"count":53},{"year":2025,"count":51},{"year":2026,"count":17}],"oa_status":"bronze","license":null,"oa_locations":[{"url":"https://www.pnas.org/content/pnas/111/22/8239.full.pdf","host_type":"journal"},{"url":"https://www.pnas.org/content/pnas/111/22/8239.full.pdf","host_type":"BRONZE"},{"url":"https://www.pnas.org/content/pnas/111/22/8239.full.pdf","host_type":"publisher"},{"url":"https://pnas.org/doi/pdf/10.1073/pnas.1402028111","host_type":"publisher"},{"url":"https://doi.org/10.1073/pnas.1402028111","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/24843170","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4050595","host_type":"repository"},{"url":"https://dx.doi.org/10.1073/pnas.1402028111","host_type":""},{"url":"https://sonar.ch/global/documents/253817","host_type":""},{"url":"http://hdl.handle.net/21.11116/0000-000A-CB10-F","host_type":""},{"url":"http://dx.doi.org/10.1073/pnas.1402028111","host_type":""}],"fields_of_study":["Microbial Community Ecology and Physiology","Genomics and Phylogenetic Studies","Methane Hydrates and Related Phenomena","Biology","Medicine","Environmental Science","0301 basic medicine","0303 health sciences","03 medical and health sciences","Acetyl Coenzyme A","Aerobiosis","Ammonia","Archaea","Autotrophic Processes","Carbon Cycle","Carbon Dioxide","Energy Metabolism","Evolution, Molecular","Hydro-Lyases","Oxidation-Reduction","Photosynthesis","Phylogeny"],"mesh_terms":["Acetyl Coenzyme A","Aerobiosis","Ammonia","Archaea","Carbon Dioxide","Energy Metabolism","Hydro-Lyases","Oxidation-Reduction","Photosynthesis","Phylogeny","Evolution, Molecular","Autotrophic Processes","Carbon Cycle"],"keywords":["Thaumarchaeota","Archaea","Crenarchaeota","Autotroph","Phylum","Euryarchaeota","Biology","Carbon fixation","Carbon cycle","Nitrogen cycle","Nitrogen fixation","Thermophile","Ecology","Biochemistry","Ecosystem","Chemistry","Bacteria","Nitrogen","Paleontology","Carbon dioxide","Gene","Autotrophy","Nitrosopumilus Maritimus","Autotrophic Processes","Aerobiosis","Evolution, Molecular","Acetyl Coenzyme A","Ammonia","Photosynthesis","Energy Metabolism","Oxidation-Reduction","Hydro-Lyases","Phylogeny"],"sdg_mappings":[{"sdg_number":7,"sdg_label":"7. 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