{"doi":"10.1056/nejmc1211767","title":"Clinical and Biomarker Changes in Alzheimer's Disease","abstract":null,"journal":"New England Journal of Medicine","year":2012,"id":640450,"datarank":0.26876392038420827,"base_score":1.791759469228055,"endowment":1.791759469228055,"self_citation_contribution":0.26876392038420827,"citation_network_contribution":0.0,"self_endowment_contribution":0.26876392038420827,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Clinical and Biomarker Changes in Alzheimer's Disease","abstract":"describe clinical and biomarker changes in dom-inantly inherited Alzheimer’s disease. The big question is whether our increasing knowledge about inherited Alzheimer’s disease can also be applied to sporadic Alzheimer’s disease, which occurs approximately 100 times as frequently as the inherited form of the disease. The clinical and biomarker changes in patients with inherited Alzheimer’s disease correspond quite well with what is expected to occur in sporadic Alzheimer’s disease.","is_dataset_classified":null,"base_score":1.791759469228055,"endowment":1.791759469228055,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"23171106","pmcid":null,"openalex_id":"https://openalex.org/W2407099905","authors":[],"funders":[],"total_grants":0,"fwci":0.1584,"citation_percentile":0.56166644,"influential_citations":0,"citation_trend":[{"year":2013,"count":1},{"year":2016,"count":1},{"year":2017,"count":1},{"year":2020,"count":1},{"year":2022,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"http://www.nejm.org/doi/pdf/10.1056/NEJMc1211767","host_type":"publisher"},{"url":"https://doi.org/10.1056/nejmc1211767","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/23171104","host_type":"repository"},{"url":"https://pubmed.ncbi.nlm.nih.gov/23171105","host_type":"repository"},{"url":"https://pubmed.ncbi.nlm.nih.gov/23171106","host_type":"repository"}],"fields_of_study":["Alzheimer's disease research and treatments","Dementia and Cognitive Impairment Research","Parkinson's Disease Mechanisms and Treatments","Alzheimer Disease","Amyloid beta-Peptides","Cerebrospinal Fluid","Female","Humans","Male"],"mesh_terms":["Alzheimer Disease","Cerebrospinal Fluid","Female","Humans","Male","Amyloid beta-Peptides"],"keywords":["Medicine","Biomarker","Alzheimer's disease","Disease","Pathology"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-07T11:58:05.904534Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}