{"doi":"10.1055/s-2008-1076110","title":"Validation of ECoScreen 2 for Collection of fractionated Exhaled Breath Condensate (EBC)","abstract":null,"journal":"Pneumologie","year":2008,"id":628371,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1626867,"name":"K Schulze","orcid":null,"position":1,"is_corresponding":false},{"id":972854,"name":"G Becher","orcid":"0000-0001-9836-2787","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Validation of ECoScreen 2 for Collection of fractionated Exhaled Breath Condensate (EBC)","abstract":"Introduction: Systematic analysis of markers from exhaled breath condensate (EBC) has become a more and more interesting tool for non-invasive diagnosis of lung and airway diseases. Standardization of EBC collection with respect to collection time and breathing pattern has been achieved by the development of ECoScreen and ECoVent. However, the issues on the pulmonary site in regard to the release of different markers remains still unclear. The aim of the study was to provide the technical tool to assess whether EBC markers are released from the conducting airways or the lung periphery. Methods: The ECoScreen 2 includes a trend-spirometer and a three-pneumatic-valve system to direct the exhaled air into two disposable collection bags. The valves are controlled by a pneumatic system. Breathing pattern during EBC collection is checked by a differential pressure transducer with a manifold hole-plate as resistance. The accuracy of the system is±5%. An additional task was to excrete the air from mouth cavity. Results: The system makes it possible to separate exhaled air during tidal breathing into 4 different fractions: air from the mouth cavity, air from the dead space volume (conducting airways), air from the transitional region between airways and lung parenchyma (“discarded away volume“) and air from the small airways and the alveolar space. Moreover, the total amount of EBC was higher than in all other available EBC collecting systems. Discussion: The option for free selection of EBC condensate samples from the exhaled air enables differentiation of exhaled EBC into small sized fractions. Condensing efficiency of the system is enhanced due to a longer resting time of the exhaled air in the collection bags. Ref.: Bachelor Thesis Katja Schulze, TFH Wildau: “Lokalisierung der Herkunft des Entzündungsmarkers H 2 O 2 in der Lunge durch fraktionierte Sammlung des Atemkondensates“","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19767382","pmcid":null,"openalex_id":"https://openalex.org/W2037353043","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.13248357,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":null,"oa_locations":[{"url":"http://www.thieme-connect.de/DOI/DOI?10.1055/s-2008-1076110","host_type":"publisher"},{"url":"https://doi.org/10.1055/s-2008-1076110","host_type":"journal"}],"fields_of_study":["Inhalation and Respiratory Drug Delivery","Medicine","Engineering"],"mesh_terms":[],"keywords":["Exhaled breath condensate","Medicine","Standardization","Breath gas analysis","Airway","Intensive care medicine","Pathology","Internal medicine","Asthma","Anesthesia","Computer science"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-05T13:15:53.853734Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}