{"doi":"10.1042/bst20200603","title":"Metabolic engineering for the production of butanol, a potential advanced biofuel, from renewable resources","abstract":"<jats:p>Butanol is an important chemical and potential fuel. For more than 100 years, acetone-butanol-ethanol (ABE) fermentation of Clostridium strains has been the most successful process for biological butanol production. In recent years, other microbes have been engineered to produce butanol as well, among which Escherichia coli was the best one. Considering the crude oil price fluctuation, minimizing the cost of butanol production is of highest priority for its industrial application. Therefore, using cheaper feedstocks instead of pure sugars is an important project. In this review, we summarized butanol production from different renewable resources, such as industrial and food waste, lignocellulosic biomass, syngas and other renewable resources. This review will present the current progress in this field and provide insights for further engineering efforts on renewable butanol production.</jats:p>","journal":"Biochemical Society Transactions","year":2020,"id":629671,"datarank":0.3958585994422889,"base_score":2.639057329615259,"endowment":2.639057329615259,"self_citation_contribution":0.3958585994422889,"citation_network_contribution":0.0,"self_endowment_contribution":0.3958585994422889,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":13,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":597529,"name":"Yanping Zhang","orcid":"0009-0007-0319-6095","position":1,"is_corresponding":false},{"id":32289,"name":"Yin Li","orcid":"0000-0003-4911-9208","position":2,"is_corresponding":false},{"id":1630889,"name":"Chunhua Zhao","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Metabolic engineering for the production of butanol, a potential advanced biofuel, from renewable resources","abstract":"<jats:p>Butanol is an important chemical and potential fuel. For more than 100 years, acetone-butanol-ethanol (ABE) fermentation of Clostridium strains has been the most successful process for biological butanol production. In recent years, other microbes have been engineered to produce butanol as well, among which Escherichia coli was the best one. Considering the crude oil price fluctuation, minimizing the cost of butanol production is of highest priority for its industrial application. Therefore, using cheaper feedstocks instead of pure sugars is an important project. In this review, we summarized butanol production from different renewable resources, such as industrial and food waste, lignocellulosic biomass, syngas and other renewable resources. This review will present the current progress in this field and provide insights for further engineering efforts on renewable butanol production.</jats:p>","is_dataset_classified":null,"base_score":2.5649493574615367,"endowment":2.5649493574615367,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"32897293","pmcid":null,"openalex_id":"https://openalex.org/W3084118982","authors":[],"funders":[],"total_grants":0,"fwci":0.5155,"citation_percentile":0.57956754,"influential_citations":0,"citation_trend":[{"year":2021,"count":3},{"year":2022,"count":3},{"year":2023,"count":1},{"year":2024,"count":1},{"year":2025,"count":3},{"year":2026,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://portlandpress.com/biochemsoctrans/article-pdf/48/5/2283/896587/bst-2020-0603.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1042/bst20200603","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/32897293","host_type":"repository"}],"fields_of_study":["Biofuel production and bioconversion","Microbial Metabolic Engineering and Bioproduction","Catalysis for Biomass Conversion"],"mesh_terms":["Acetone","Ethanol","Butanols","Biotechnology","Carbon","Clostridium","Electrons","Escherichia coli","Fermentation","Food","Hexoses","Hydrolysis","Models, Biological","Pentoses","Petroleum","Refuse Disposal","Sucrose","Biomass","Biofuels","Synthetic Biology","Metabolic Engineering"],"keywords":["Butanol","Biofuel","Biochemical engineering","Renewable resource","Renewable energy","Metabolic engineering","Biomass (ecology)","Lignocellulosic biomass","Renewable fuels","Production (economics)","Fossil fuel","Environmental science","Biotechnology","Pulp and paper industry","Waste management","Chemistry","Engineering","Ethanol","Economics","Biology","Ecology","Organic chemistry","Renewable resources"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Responsible consumption and production"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-05T19:22:48.403333Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}