{"doi":"10.1042/bst0280464","title":"Exploring the <i>Caenorhabditis elegans</i> and <i>Drosophila melanogaster</i> genomes to understand neuropeptide and peptidase function","abstract":"<jats:p>Comparison of peptidase gene families in the newly released Drosophila melanogaster and Caenorhabditis elegans genomes highlights important differences in peptidase distributions with relevance to the evolution of both form and function in these two organisms and can help to identify the most appropriate model when using comparative studies relevant to the human condition.</jats:p>","journal":"Biochemical Society Transactions","year":2000,"id":592568,"datarank":1.6461597453108228,"base_score":3.5263605246161616,"endowment":3.5263605246161616,"self_citation_contribution":0.5289540786924243,"citation_network_contribution":1.1172056666183985,"self_endowment_contribution":0.5289540786924243,"citer_contribution":1.1172056666183985,"corpus_percentile":null,"corpus_rank":null,"citation_count":33,"citer_count":29,"citers_with_citation_signal":28,"citers_with_endowment":28,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1516362,"name":"R. Siviter","orcid":null,"position":1,"is_corresponding":false},{"id":1516363,"name":"R. E. Isaac","orcid":null,"position":2,"is_corresponding":false},{"id":1516361,"name":"D. Coates","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Exploring the <i>Caenorhabditis elegans</i> and <i>Drosophila melanogaster</i> genomes to understand neuropeptide and peptidase function","abstract":"<jats:p>Comparison of peptidase gene families in the newly released Drosophila melanogaster and Caenorhabditis elegans genomes highlights important differences in peptidase distributions with relevance to the evolution of both form and function in these two organisms and can help to identify the most appropriate model when using comparative studies relevant to the human condition.</jats:p>","is_dataset_classified":null,"base_score":3.5263605246161616,"endowment":3.5263605246161616,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"10961941","pmcid":null,"openalex_id":"https://openalex.org/W1980411169","authors":[],"funders":[],"total_grants":0,"fwci":0.8554,"citation_percentile":0.71610852,"influential_citations":0,"citation_trend":[{"year":2012,"count":1},{"year":2013,"count":3},{"year":2014,"count":3},{"year":2017,"count":4},{"year":2021,"count":1},{"year":2023,"count":1},{"year":2025,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://portlandpress.com/biochemsoctrans/article-pdf/28/4/464/526377/bst0280464.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1042/bst0280464","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/10961941","host_type":"repository"}],"fields_of_study":["Protein Hydrolysis and Bioactive Peptides","Peptidase Inhibition and Analysis","Neuropeptides and Animal Physiology"],"mesh_terms":["Animals","Drosophila melanogaster","Invertebrates","Peptidyl-Dipeptidase A","Metalloendopeptidases","Neuropeptides","Peptide Hydrolases","Phenotype","Phylogeny","Serine Endopeptidases","Zinc","Neprilysin","Genome","Caenorhabditis elegans","Matrix Metalloproteinases"],"keywords":["Drosophila melanogaster","Caenorhabditis elegans","Biology","Genome","Melanogaster","Caenorhabditis","Model organism","Function (biology)","Drosophila (subgenus)","Gene","Genetics","Computational biology","Evolutionary biology"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-26T14:15:04.818102Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}