{"doi":"10.1039/d4ra05594b","title":"Antimicrobial bianthrones from the crinoid <i>Heterometra</i> sp.","abstract":"sp. (Echinodermata), showed antibacterial activity. Chemical investigation of this extract led to the isolation of three natural products, namely crinemodin bianthrone (1), the new structure 1''-dehydrocrinemodin bianthrone (2), and 1''-hydroxycrinemodin bianthrone (3). Their planar structures were determined through HRESIMS and 1D and 2D NMR analysis while a combination of chemical and chirooptical methods was employed to define their absolute configurations for the first time. Variations in proton chemical shifts as well as instability in DMSO and pyridine were observed for 3. Compounds 1 and 3 showed selective antimicrobial activity against Gram-positive bacterial strains.","journal":"RSC Advances","year":2024,"id":451070,"datarank":0.24141568686511508,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.0,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9504,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1041900,"name":"Lucero Martínez-Fructuoso","orcid":"0000-0002-2279-5479","position":1,"is_corresponding":false},{"id":1041903,"name":"Rohitesh Kumar","orcid":"0000-0002-7187-937X","position":2,"is_corresponding":false},{"id":297114,"name":"Rhone K. Akee","orcid":null,"position":3,"is_corresponding":false},{"id":257549,"name":"Christopher C. Thornburg","orcid":"0000-0002-4657-6895","position":4,"is_corresponding":false},{"id":296328,"name":"Susan M. Ensel","orcid":"0000-0002-7733-1065","position":5,"is_corresponding":false},{"id":1272507,"name":"Ekene Okoroafor","orcid":null,"position":6,"is_corresponding":false},{"id":297117,"name":"Jason R. Evans","orcid":null,"position":7,"is_corresponding":false},{"id":422588,"name":"Dongdong Wang","orcid":"0000-0002-7824-2507","position":8,"is_corresponding":false},{"id":952371,"name":"Brian D. Peyser","orcid":"0000-0002-3455-5181","position":9,"is_corresponding":false},{"id":257551,"name":"Tanja Grkovic","orcid":"0000-0002-6537-3997","position":10,"is_corresponding":false},{"id":257552,"name":"Barry R. O’Keefe","orcid":"0000-0003-0772-4856","position":11,"is_corresponding":false},{"id":1041902,"name":"Vítor F. Freire","orcid":"0000-0001-6565-1830","position":0,"is_corresponding":true}],"reference_count":19,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T02:02:41.417944Z","pmid":"39624437","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}