{"doi":"10.1039/d2cc05668b","title":"CAAC–IPr*: easily accessible, highly sterically-hindered cyclic (alkyl)(amino)carbenes","abstract":"IPr* (IPr* = 1,3-bis(2,6-bis(diphenylmethyl)-4-methylphenyl)imidazol-2-ylidene) has emerged as a powerful highly hindered and sterically-flexible ligand platform for transition-metal catalysis. CAACs (CAAC = cyclic (al-kyl)(amino)carbenes) have gained major attention as strongly electron-rich carbon analogues of NHCs (NHC = N-heterocyclic carbene) with broad applications in both industry and academia. Herein, we report a merger of CAAC ligands with highly-hindered IPr*. The efficient synthesis, electronic characterization and application in model Cu-catalyzed hydroboration of alkynes is described. The ligands are strongly electron-rich, bulky and flexible around the N-Ar wingtip. The availability of various IPr* and CAAC templates offers a significant potential to expand the existing arsenal of NHC ligands to electron-rich bulky architectures with critical applications in metal stabilization and catalysis.","journal":"Chemical Communications","year":2022,"id":253895,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":22,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9557,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":292008,"name":"Tongliang Zhou","orcid":"0000-0002-7334-7078","position":1,"is_corresponding":false},{"id":887037,"name":"Elwira Bisz","orcid":"0000-0002-7070-2468","position":2,"is_corresponding":false},{"id":887038,"name":"Błażej Dziuk","orcid":"0000-0003-1593-2719","position":3,"is_corresponding":false},{"id":641131,"name":"Roger A. Lalancette","orcid":"0000-0002-3470-532X","position":4,"is_corresponding":false},{"id":641132,"name":"Roman Szostak","orcid":"0000-0002-5436-7284","position":5,"is_corresponding":false},{"id":240705,"name":"Michal Szostak","orcid":"0000-0002-9650-9690","position":6,"is_corresponding":false},{"id":899982,"name":"Wen-Chao Chu","orcid":"0000-0002-7815-0514","position":0,"is_corresponding":true}],"reference_count":45,"raw_metadata":null,"created_at":"2026-07-19T00:24:59.596040Z","pmid":"36382995","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}