{"doi":"10.1039/d0sc02020f","title":"Quinone methide dimers lacking labile hydrogen atoms are surprisingly excellent radical-trapping antioxidants","abstract":"100-fold less reactive than the QMDs, ruling out mechanism 3. These facts, combined with the poor RTA activity we observe for a QMD with a stronger central C-C bond, support mechanism 4. The lack of solvent effects on the RTA activity of QMDs suggests that they may find application as additives to materials which contain H-bonding accepting moieties that can dramatically suppress the reactivity of conventional RTAs, such as phenols. This reactivity does not extend to biological membranes owing to the increased microviscosity of the phospholipid bilayer, which suppresses QMD dissociation in favour of recombination. Interestingly, the simple QMs were found to be very good RTAs in phospholipid bilayers - besting even the most potent form of vitamin E.","journal":"Chemical Science","year":2020,"id":78650,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":17,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9587,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":409185,"name":"Jean‐Philippe R. Chauvin","orcid":"0000-0001-8771-7968","position":1,"is_corresponding":false},{"id":409186,"name":"Matthew S. Galliher","orcid":"0000-0002-5597-3526","position":2,"is_corresponding":false},{"id":409187,"name":"Kevin Romero","orcid":"0000-0001-7604-3996","position":3,"is_corresponding":false},{"id":273785,"name":"Corey R. J. Stephenson","orcid":"0000-0002-2443-5514","position":4,"is_corresponding":false},{"id":409188,"name":"Derek A. Pratt","orcid":"0000-0002-7305-745X","position":5,"is_corresponding":false},{"id":409184,"name":"Mark A. R. Raycroft","orcid":"0000-0002-4413-409X","position":0,"is_corresponding":true}],"reference_count":44,"raw_metadata":null,"created_at":"2026-07-18T21:50:09.793321Z","pmid":"32832049","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}