{"doi":"10.1038/srep29897","title":"Acetylome analysis reveals the involvement of lysine acetylation in diverse biological processes in Phytophthora sojae","abstract":"<jats:title>Abstract</jats:title><jats:p>Lysine acetylation is a dynamic and highly conserved post-translational modification that plays an important regulatory role in almost every aspects of cell metabolism in both eukaryotes and prokaryotes. <jats:italic>Phytophthora sojae</jats:italic> is one of the most important plant pathogens due to its huge economic impact. However, to date, little is known about the functions of lysine acetylation in this Phytopthora. Here, we conducted a lysine acetylome in <jats:italic>P. sojae</jats:italic>. Overall, 2197 lysine acetylation sites in 1150 proteins were identified. The modified proteins are involved in diverse biological processes and are localized to multiple cellular compartments. Importantly, 7 proteins involved in the pathogenicity or the secretion pathway of <jats:italic>P. sojae</jats:italic> were found to be acetylated. These data provide the first comprehensive view of the acetylome of <jats:italic>P. sojae</jats:italic> and serve as an important resource for functional analysis of lysine acetylation in plant pathogens.</jats:p>","journal":"Scientific Reports","year":2016,"id":14519,"datarank":1.4720239709337237,"base_score":3.7376696182833684,"endowment":3.7376696182833684,"self_citation_contribution":0.5606504427425053,"citation_network_contribution":0.9113735281912185,"self_endowment_contribution":0.5606504427425053,"citer_contribution":0.9113735281912185,"corpus_percentile":null,"corpus_rank":null,"citation_count":41,"citer_count":31,"citers_with_citation_signal":26,"citers_with_endowment":26,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":114329,"name":"Binna Lv","orcid":null,"position":1,"is_corresponding":false},{"id":114330,"name":"Lingling Tan","orcid":null,"position":2,"is_corresponding":false},{"id":114331,"name":"Qianqian Yang","orcid":null,"position":3,"is_corresponding":false},{"id":114332,"name":"Wenxing Liang","orcid":null,"position":4,"is_corresponding":false},{"id":114328,"name":"Delong Li","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":3.7376696182833684,"endowment":3.7376696182833684,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"27412925","pmcid":"PMC4944153","openalex_id":"https://openalex.org/W2463509995","authors":[],"funders":[],"total_grants":0,"fwci":1.8865,"citation_percentile":0.87344637,"influential_citations":1,"citation_trend":[{"year":2016,"count":1},{"year":2017,"count":4},{"year":2018,"count":3},{"year":2019,"count":4},{"year":2020,"count":8},{"year":2021,"count":6},{"year":2022,"count":4},{"year":2023,"count":5},{"year":2024,"count":1},{"year":2025,"count":3},{"year":2026,"count":2}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://www.nature.com/articles/srep29897.pdf","host_type":"journal"},{"url":"https://www.nature.com/articles/srep29897.pdf","host_type":"GOLD"},{"url":"https://www.nature.com/articles/srep29897.pdf","host_type":"publisher"},{"url":"https://www.nature.com/articles/srep29897","host_type":"publisher"},{"url":"https://doi.org/10.1038/srep29897","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/27412925","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4944153","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC4944153","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC4944153?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Peptidase Inhibition and Analysis","Polyamine Metabolism and Applications","Plant-Microbe Interactions and Immunity","Biology","Medicine","Environmental Science","Acetylation","Amino Acid Sequence","Gene Ontology","Gene Regulatory Networks","Lysine","Molecular Sequence Annotation","Mycelium","Phytophthora","Plant Diseases","Plants","Protein Interaction Mapping","Protein Processing, Post-Translational","Proteome","Virulence"],"mesh_terms":["Acetylation","Amino Acid Sequence","Lysine","Phytophthora","Plant Diseases","Plants","Protein Processing, Post-Translational","Virulence","Proteome","Mycelium","Protein Interaction Mapping","Gene Regulatory Networks","Molecular Sequence Annotation","Gene Ontology"],"keywords":["Acetylation","Lysine","Phytophthora sojae","Biology","Secretion","Biochemistry","Gene","Amino acid"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"uniprot"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-01T11:25:46.363963Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}