{"doi":"10.1038/sj.tpj.6500094","title":"Progress in high throughput SNP genotyping methods","abstract":null,"journal":"The Pharmacogenomics Journal","year":2002,"id":47318,"datarank":8.621021967681344,"base_score":5.030437921392435,"endowment":5.030437921392435,"self_citation_contribution":0.7545656882088654,"citation_network_contribution":7.866456279472479,"self_endowment_contribution":0.7545656882088654,"citer_contribution":7.866456279472479,"corpus_percentile":null,"corpus_rank":null,"citation_count":152,"citer_count":142,"citers_with_citation_signal":123,"citers_with_endowment":123,"datacite_reuse_total":10,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":218754,"name":"N C Dracopoli","orcid":null,"position":1,"is_corresponding":false},{"id":218753,"name":"Z Tsuchihashi","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Progress in high throughput SNP genotyping methods","abstract":"Most current single nucleotide polymorphism (SNP) genotyping methods are still too slow and expensive for routine use in large association studies with hundreds or more SNPs in a large number of DNA samples. However, SNP genotyping technology is rapidly progressing with the emergence of novel, faster and cheaper methods as well as improvements in the existing methods. In this review, we focus on technologies aimed at high throughput uses, and discuss the technical advances made in this field in the last few years. The rapid progress in technology, in combination with the discovery of millions of SNPs and the development of the human haplotype map, may enable whole genome association studies to be initiated in the near future.","is_dataset_classified":null,"base_score":5.030437921392435,"endowment":5.030437921392435,"datacite_reuse_total":10,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"12049172","pmcid":null,"openalex_id":"https://openalex.org/W2038717263","authors":[],"funders":[],"total_grants":0,"fwci":3.0625,"citation_percentile":0.91993587,"influential_citations":2,"citation_trend":[{"year":2012,"count":11},{"year":2013,"count":9},{"year":2014,"count":4},{"year":2015,"count":4},{"year":2016,"count":5},{"year":2017,"count":2},{"year":2018,"count":3},{"year":2019,"count":3},{"year":2020,"count":5},{"year":2021,"count":7},{"year":2022,"count":1},{"year":2023,"count":3},{"year":2024,"count":14},{"year":2025,"count":6}],"oa_status":"closed","license":"https://www.springer.com/tdm","oa_locations":[{"url":"https://www.nature.com/articles/6500094.pdf","host_type":"BRONZE"},{"url":"https://www.nature.com/articles/6500094","host_type":"publisher"},{"url":"https://doi.org/10.1038/sj.tpj.6500094","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/12049172","host_type":"repository"}],"fields_of_study":["Gene expression and cancer classification","Molecular Biology Techniques and Applications","RNA and protein synthesis mechanisms","Biology","Medicine","Animals","Genomics","Genotype","Humans","Polymorphism, Single Nucleotide"],"mesh_terms":["Animals","Genotype","Humans","Polymorphism, Single Nucleotide","Genomics"],"keywords":["Genotyping","Single-nucleotide polymorphism","SNP","SNP genotyping","Computational biology","Haplotype","Tag SNP","Biology","SNP array","Genetic association","Human genome","Genome-wide association study","Genetics","Genome","Computer science","Genotype","Gene"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Industry, innovation and infrastructure"}],"linked_datasets":[{"doi":"10.6084/m9.figshare.26666617.v1","title":"Additional file 1 of Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26666617","title":"Additional file 1 of Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26666620.v1","title":"Additional file 2 of Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26666623.v1","title":"Additional file 3 of Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26666620","title":"Additional file 2 of Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26666623","title":"Additional file 3 of Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26666626.v1","title":"Additional file 4 of Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26666626","title":"Additional file 4 of Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26666629.v1","title":"Additional file 5 of Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26666629","title":"Additional file 5 of Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China","publisher":"figshare","resource_type":"JournalArticle"}],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-18T15:21:23.986053Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}