{"doi":"10.1038/s41598-023-32441-7","title":"Analysis of fatality impact and seroprevalence surveys in a community sustaining a SARS-CoV-2 superspreading event","abstract":"There is an ongoing debate on the COVID-19 infection fatality rate (IFR) and the impact of COVID-19 on overall population mortality. Here, we addressed these issues in a community in Germany with a major superspreader event analyzing deaths over time and auditing death certificates in the community.18 deaths that occurred within the first six months of the pandemic had a positive test for SARS-CoV-2. Six out of 18 deaths had non-COVID-19 related causes of death (COD). Individuals with COVID-19 COD typically died of respiratory failure (75%) and tended to have fewer reported comorbidities (p = 0.029). Duration between first confirmed infection and death was negatively associated with COVID-19 being COD (p = 0.04). Repeated seroprevalence essays in a cross-sectional epidemiological study showed modest increases in seroprevalence over time, and substantial seroreversion (30%). IFR estimates accordingly varied depending on COVID-19 death attribution. Careful ascertainment of COVID-19 deaths is important in understanding the impact of the pandemic.","journal":"Scientific Reports","year":2023,"id":7593,"datarank":0.20794415416798362,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"self_citation_contribution":0.20794415416798362,"citation_network_contribution":0.0,"self_endowment_contribution":0.20794415416798362,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.0496,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-04-03","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":64603,"name":"Dominik Liebl","orcid":"0000-0002-9282-4394","position":1,"is_corresponding":false},{"id":64604,"name":"Bianca Schulte","orcid":"0000-0003-1096-3751","position":2,"is_corresponding":false},{"id":64605,"name":"Nils Lehmann","orcid":"0000-0003-2395-8708","position":3,"is_corresponding":false},{"id":64606,"name":"Christine Fuhrmann","orcid":"0009-0004-1527-145X","position":4,"is_corresponding":false},{"id":6218,"name":"Karl-Heinz Jöckel","orcid":null,"position":5,"is_corresponding":false},{"id":148,"name":"John P. A. Ioannidis","orcid":"0000-0003-3118-6859","position":6,"is_corresponding":false},{"id":64607,"name":"Hendrik Streeck","orcid":"0000-0002-0335-6390","position":7,"is_corresponding":false},{"id":6231,"name":"Karl‐Heinz Jöckel","orcid":"0000-0002-1987-0255","position":8,"is_corresponding":false},{"id":64602,"name":"Enrico Richter","orcid":"0009-0008-7736-8053","position":0,"is_corresponding":true}],"reference_count":52,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-03-01T18:20:47.508186Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}