{"doi":"10.1038/s41577-021-00534-x","title":"The inflammatory pathogenesis of colorectal cancer","abstract":null,"journal":"Nature Reviews Immunology","year":2021,"id":639765,"datarank":8.396541094676465,"base_score":6.664409020350408,"endowment":6.664409020350408,"self_citation_contribution":0.9996613530525613,"citation_network_contribution":7.396879741623903,"self_endowment_contribution":0.9996613530525613,"citer_contribution":7.396879741623903,"corpus_percentile":null,"corpus_rank":null,"citation_count":783,"citer_count":200,"citers_with_citation_signal":200,"citers_with_endowment":200,"datacite_reuse_total":25,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":50572,"name":"Florian R. 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Here, we review our current understanding of how colon cancer cells interact with their microenvironment, comprised of immune cells, stromal cells and the intestinal microbiome, to suppress or escape immune responses and how inflammatory processes shape the immune pathogenesis of 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Immunotherapy and Biomarkers","Immune Cell Function and Interaction","Immune cells in cancer","Medicine","Biology","Environmental Science","Animals","Cell Transformation, Neoplastic","Colorectal Neoplasms","Gastrointestinal Microbiome","Humans","Inflammation","Stromal Cells","Tumor Microenvironment"],"mesh_terms":["Gastrointestinal Microbiome","Animals","Cell Transformation, Neoplastic","Humans","Inflammation","Colorectal Neoplasms","Stromal Cells","Tumor Microenvironment"],"keywords":["Immune system","Stromal cell","Tumor microenvironment","Colorectal cancer","Pathogenesis","Cancer research","Carcinogenesis","Immunology","Biology","Mouse model of colorectal and intestinal cancer","Cancer","Inflammation","Medicine","Genetics"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[{"doi":"10.6084/m9.figshare.25036273.v1","title":"Additional file 1 of MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose 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