{"doi":"10.1038/nsmb885","title":"Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex","abstract":null,"journal":"Nature Structural & Molecular Biology","year":2005,"id":24765,"datarank":6.931571816603238,"base_score":5.043425116919247,"endowment":5.043425116919247,"self_citation_contribution":0.7565137675378871,"citation_network_contribution":6.175058049065351,"self_endowment_contribution":0.7565137675378871,"citer_contribution":6.175058049065351,"corpus_percentile":null,"corpus_rank":null,"citation_count":154,"citer_count":139,"citers_with_citation_signal":124,"citers_with_endowment":124,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":147622,"name":"Xitong Yuan","orcid":null,"position":1,"is_corresponding":false},{"id":147623,"name":"Zhexin Xiang","orcid":null,"position":2,"is_corresponding":false},{"id":147624,"name":"Edward Mimnaugh","orcid":null,"position":3,"is_corresponding":false},{"id":147625,"name":"Monica Marcu","orcid":null,"position":4,"is_corresponding":false},{"id":142054,"name":"Len Neckers","orcid":null,"position":5,"is_corresponding":false},{"id":147620,"name":"Wanping Xu","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":5.043425116919247,"endowment":5.043425116919247,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"15643424","pmcid":null,"openalex_id":"https://openalex.org/W1994485012","authors":[],"funders":[],"total_grants":0,"fwci":5.8128,"citation_percentile":0.96952909,"influential_citations":10,"citation_trend":[{"year":2012,"count":4},{"year":2013,"count":13},{"year":2014,"count":2},{"year":2015,"count":4},{"year":2016,"count":7},{"year":2017,"count":5},{"year":2018,"count":5},{"year":2019,"count":6},{"year":2020,"count":3},{"year":2021,"count":6},{"year":2022,"count":7},{"year":2023,"count":8},{"year":2024,"count":4},{"year":2025,"count":5}],"oa_status":"closed","license":"http://www.springer.com/tdm","oa_locations":[{"url":"http://www.nature.com/articles/nsmb885.pdf","host_type":"publisher"},{"url":"http://www.nature.com/articles/nsmb885","host_type":"publisher"},{"url":"https://doi.org/10.1038/nsmb885","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/15643424","host_type":"repository"}],"fields_of_study":["Heat shock proteins research","Toxin Mechanisms and Immunotoxins","Protein Structure and Dynamics","Biology","Medicine","Chemistry","Animals","Benzoquinones","COS Cells","Cell Line, Tumor","ErbB Receptors","HSP90 Heat-Shock Proteins","Humans","Hydrophobic and Hydrophilic Interactions","Lactams, Macrocyclic","Models, Molecular","Multiprotein Complexes","Mutation","Protein Binding","Protein Structure, Tertiary","Quinones","Erb-b2 Receptor Tyrosine Kinases","Static Electricity"],"mesh_terms":["Animals","Humans","Models, Molecular","Mutation","Protein Binding","Quinones","Benzoquinones","Protein Structure, Tertiary","Receptor, ErbB-2","Erb-b2 Receptor Tyrosine Kinases","HSP90 Heat-Shock Proteins","COS Cells","Cell Line, Tumor","Multiprotein Complexes","Lactams, Macrocyclic","Static Electricity","Hydrophobic and Hydrophilic Interactions","ErbB Receptors"],"keywords":["Hsp90","Geldanamycin","Chaperone (clinical)","CDC37","Cell biology","Mutant","Biology","Plasma protein binding","Point mutation","Kinase","Co-chaperone","Binding site","Biochemistry","Chemistry","Heat shock protein","Gene"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-07T23:11:22.359363Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}