{"doi":"10.1038/nprot.2008.211","title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","abstract":"DAVID bioinformatics resources consists of an integrated biological knowledgebase and analytic tools aimed at systematically extracting biological meaning from large gene/protein lists. This protocol explains how to use DAVID, a high-throughput and integrated data-mining environment, to analyze gene lists derived from high-throughput genomic experiments. The procedure first requires uploading a gene list containing any number of common gene identifiers followed by analysis using one or more text and pathway-mining tools such as gene functional classification, functional annotation chart or clustering and functional annotation table. By following this protocol, investigators are able to gain an in-depth understanding of the biological themes in lists of genes that are enriched in genome-scale studies.","journal":"Nature Protocols","year":2008,"id":12226,"datarank":26.727388084561035,"base_score":10.512682309099187,"endowment":10.512682309099187,"self_citation_contribution":1.5769023463648784,"citation_network_contribution":25.150485738196156,"self_endowment_contribution":1.5769023463648784,"citer_contribution":25.150485738196156,"corpus_percentile":100.0,"corpus_rank":116,"citation_count":36778,"citer_count":198,"citers_with_citation_signal":198,"citers_with_endowment":198,"datacite_reuse_total":0,"is_dataset":true,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2008-12-18","authors":[{"id":60621,"name":"Brad T. Sherman","orcid":"0000-0001-5815-7359","position":1,"is_corresponding":false},{"id":60625,"name":"Richard A. Lempicki","orcid":"0000-0002-7059-409X","position":2,"is_corresponding":false},{"id":96765,"name":"Da Wei Huang","orcid":"0000-0002-6793-9966","position":0,"is_corresponding":true}],"reference_count":16,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-03-01T18:20:47.508186Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}